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Surgery's role in contemporary osteoarticular infection management

The treatment paradigm for osteoarticular infections (OAIs) has changed drastically over the past 80 years, from the advent of penicillin to the use of broad-spectrum antibiotics. Before these drugs, surgery was the only available treatment for OAIs; today, antibiotic therapy is considered the prima...

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Autores principales: De Marco, Giacomo, Vazquez, Oscar, Gavira, Nathaly, Ramadani, Ardian, Steiger, Christina, Dayer, Romain, Ceroni, Dimitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806351/
https://www.ncbi.nlm.nih.gov/pubmed/36601031
http://dx.doi.org/10.3389/fped.2022.1043251
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author De Marco, Giacomo
Vazquez, Oscar
Gavira, Nathaly
Ramadani, Ardian
Steiger, Christina
Dayer, Romain
Ceroni, Dimitri
author_facet De Marco, Giacomo
Vazquez, Oscar
Gavira, Nathaly
Ramadani, Ardian
Steiger, Christina
Dayer, Romain
Ceroni, Dimitri
author_sort De Marco, Giacomo
collection PubMed
description The treatment paradigm for osteoarticular infections (OAIs) has changed drastically over the past 80 years, from the advent of penicillin to the use of broad-spectrum antibiotics. Before these drugs, surgery was the only available treatment for OAIs; today, antibiotic therapy is considered the primary response to them. As a result, surgical treatment of OAIs is thus far more rarely indicated, sometimes even considered outdated and obsolete. However, long experience has taught us that many OAI contexts can still benefit from surgical management, constituting an essential complement to medical treatment. The present article seeks to contextualize this discussion by providing a chronological review of the surgical treatments used in cases of OAI and describing the quality of evidence supporting their rehabilitation in well-established situations.
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spelling pubmed-98063512023-01-03 Surgery's role in contemporary osteoarticular infection management De Marco, Giacomo Vazquez, Oscar Gavira, Nathaly Ramadani, Ardian Steiger, Christina Dayer, Romain Ceroni, Dimitri Front Pediatr Pediatrics The treatment paradigm for osteoarticular infections (OAIs) has changed drastically over the past 80 years, from the advent of penicillin to the use of broad-spectrum antibiotics. Before these drugs, surgery was the only available treatment for OAIs; today, antibiotic therapy is considered the primary response to them. As a result, surgical treatment of OAIs is thus far more rarely indicated, sometimes even considered outdated and obsolete. However, long experience has taught us that many OAI contexts can still benefit from surgical management, constituting an essential complement to medical treatment. The present article seeks to contextualize this discussion by providing a chronological review of the surgical treatments used in cases of OAI and describing the quality of evidence supporting their rehabilitation in well-established situations. Frontiers Media S.A. 2022-12-19 /pmc/articles/PMC9806351/ /pubmed/36601031 http://dx.doi.org/10.3389/fped.2022.1043251 Text en © 2022 De Marco, Vazquez, Gavira, Ramadani, Steiger, Dayer and Ceroni. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY) (https://creativecommons.org/licenses/by/4.0/) . The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
De Marco, Giacomo
Vazquez, Oscar
Gavira, Nathaly
Ramadani, Ardian
Steiger, Christina
Dayer, Romain
Ceroni, Dimitri
Surgery's role in contemporary osteoarticular infection management
title Surgery's role in contemporary osteoarticular infection management
title_full Surgery's role in contemporary osteoarticular infection management
title_fullStr Surgery's role in contemporary osteoarticular infection management
title_full_unstemmed Surgery's role in contemporary osteoarticular infection management
title_short Surgery's role in contemporary osteoarticular infection management
title_sort surgery's role in contemporary osteoarticular infection management
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806351/
https://www.ncbi.nlm.nih.gov/pubmed/36601031
http://dx.doi.org/10.3389/fped.2022.1043251
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