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Clinically relevant fusion oncogenes: detection and practical implications

Mechanistically, chimeric genes result from DNA rearrangements and include parts of preexisting normal genes combined at the genomic junction site. Some rearranged genes encode pathological proteins with altered molecular functions. Those which can aberrantly promote carcinogenesis are called fusion...

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Detalles Bibliográficos
Autores principales:	Sorokin, Maksim, Rabushko, Elizaveta, Rozenberg, Julian Markovich, Mohammad, Tharaa, Seryakov, Aleksander, Sekacheva, Marina, Buzdin, Anton
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Using RNA Sequencing and Profiling in Diagnosis and Treatment of Cancer
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806411/ https://www.ncbi.nlm.nih.gov/pubmed/36601633 http://dx.doi.org/10.1177/17588359221144108

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