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Gender gaps in type 1 diabetes care

AIMS: Diabetes mellitus is one of the largest global health concerns of recent times. Women with diabetes mellitus have a higher excess risk of all-cause mortality and more vascular events than men. Focusing on type 1 diabetes, this could be caused by gender inequalities in delivered diabetes care....

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Autores principales: Bak, Jessica C. G., Serné, Erik H., de Valk, Harold W., Valk, Niek K., Kramer, Mark H. H., Nieuwdorp, Max, Verheugt, Carianne L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Milan 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806805/
https://www.ncbi.nlm.nih.gov/pubmed/36592220
http://dx.doi.org/10.1007/s00592-022-02023-6
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author Bak, Jessica C. G.
Serné, Erik H.
de Valk, Harold W.
Valk, Niek K.
Kramer, Mark H. H.
Nieuwdorp, Max
Verheugt, Carianne L.
author_facet Bak, Jessica C. G.
Serné, Erik H.
de Valk, Harold W.
Valk, Niek K.
Kramer, Mark H. H.
Nieuwdorp, Max
Verheugt, Carianne L.
author_sort Bak, Jessica C. G.
collection PubMed
description AIMS: Diabetes mellitus is one of the largest global health concerns of recent times. Women with diabetes mellitus have a higher excess risk of all-cause mortality and more vascular events than men. Focusing on type 1 diabetes, this could be caused by gender inequalities in delivered diabetes care. This study aims to assess gender differences in type 1 diabetes outpatient care, particularly diagnostics and outcomes. METHODS: This cross-sectional cohort study included all adult type 1 diabetes patients in the Dutch Pediatric and Adult Registry of Diabetes (DPARD) visiting diabetes outpatient clinics between 2016–2021. The frequency of process measurements, including physical examination and laboratory testing, was assessed among both sexes after adjustment for age and body mass index. Gender differences in eGFR ≥ 60, BMI-, and control in blood pressure and LDL-cholesterol were evaluated. Hospital variation in achieving HbA1c targets of 53 mmol/mol and median HbA1c were assessed. Cardiovascular risk scores were calculated in men and women using the Systematic Coronary Risk Evaluation (SCORE) European low-risk chart. RESULTS: Our study showed a 17% higher odds of reaching weight control and a 23% lower odds of achieving blood pressure targets in men than women. Gender-skewed cardiovascular mortality risk scores were found. Gender disparities in outcomes appear not to be caused by gender-biased attitudes in healthcare professionals since no gender differences were found in the performance of process measurements in type 1 diabetes care. In addition, hospitals appear to vary by extent of gender differences in achieving a target HbA1c of 53 mmol/mol. CONCLUSION: Gender equality exists in the diagnostic process of diabetes care. However, differences in weight control, blood pressure control, and cardiovascular mortality risk scores remain between both sexes, most likely due to multifactorial causes. Indications for interhospital variation in gender disparities in HbA1c control exist. Further focus on performance of process measurements between hospitals may identify areas for improvement of gender-skewed outcomes to further enhance Dutch diabetes care for both sexes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00592-022-02023-6.
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spelling pubmed-98068052023-01-04 Gender gaps in type 1 diabetes care Bak, Jessica C. G. Serné, Erik H. de Valk, Harold W. Valk, Niek K. Kramer, Mark H. H. Nieuwdorp, Max Verheugt, Carianne L. Acta Diabetol Original Article AIMS: Diabetes mellitus is one of the largest global health concerns of recent times. Women with diabetes mellitus have a higher excess risk of all-cause mortality and more vascular events than men. Focusing on type 1 diabetes, this could be caused by gender inequalities in delivered diabetes care. This study aims to assess gender differences in type 1 diabetes outpatient care, particularly diagnostics and outcomes. METHODS: This cross-sectional cohort study included all adult type 1 diabetes patients in the Dutch Pediatric and Adult Registry of Diabetes (DPARD) visiting diabetes outpatient clinics between 2016–2021. The frequency of process measurements, including physical examination and laboratory testing, was assessed among both sexes after adjustment for age and body mass index. Gender differences in eGFR ≥ 60, BMI-, and control in blood pressure and LDL-cholesterol were evaluated. Hospital variation in achieving HbA1c targets of 53 mmol/mol and median HbA1c were assessed. Cardiovascular risk scores were calculated in men and women using the Systematic Coronary Risk Evaluation (SCORE) European low-risk chart. RESULTS: Our study showed a 17% higher odds of reaching weight control and a 23% lower odds of achieving blood pressure targets in men than women. Gender-skewed cardiovascular mortality risk scores were found. Gender disparities in outcomes appear not to be caused by gender-biased attitudes in healthcare professionals since no gender differences were found in the performance of process measurements in type 1 diabetes care. In addition, hospitals appear to vary by extent of gender differences in achieving a target HbA1c of 53 mmol/mol. CONCLUSION: Gender equality exists in the diagnostic process of diabetes care. However, differences in weight control, blood pressure control, and cardiovascular mortality risk scores remain between both sexes, most likely due to multifactorial causes. Indications for interhospital variation in gender disparities in HbA1c control exist. Further focus on performance of process measurements between hospitals may identify areas for improvement of gender-skewed outcomes to further enhance Dutch diabetes care for both sexes. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00592-022-02023-6. Springer Milan 2023-01-02 2023 /pmc/articles/PMC9806805/ /pubmed/36592220 http://dx.doi.org/10.1007/s00592-022-02023-6 Text en © Springer-Verlag Italia S.r.l., part of Springer Nature 2023, Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law. This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic.
spellingShingle Original Article
Bak, Jessica C. G.
Serné, Erik H.
de Valk, Harold W.
Valk, Niek K.
Kramer, Mark H. H.
Nieuwdorp, Max
Verheugt, Carianne L.
Gender gaps in type 1 diabetes care
title Gender gaps in type 1 diabetes care
title_full Gender gaps in type 1 diabetes care
title_fullStr Gender gaps in type 1 diabetes care
title_full_unstemmed Gender gaps in type 1 diabetes care
title_short Gender gaps in type 1 diabetes care
title_sort gender gaps in type 1 diabetes care
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806805/
https://www.ncbi.nlm.nih.gov/pubmed/36592220
http://dx.doi.org/10.1007/s00592-022-02023-6
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