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PD-1(high)CXCR5(–)CD4(+) peripheral helper T cells promote CXCR3(+) plasmablasts in human acute viral infection
T cell-B cell interaction is the key immune response to protect the host from severe viral infection. However, how T cells support B cells to exert protective humoral immunity in humans is not well understood. Here, we use COVID-19 as a model of acute viral infections and analyze CD4(+) T cell subse...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Authors.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806868/ https://www.ncbi.nlm.nih.gov/pubmed/36596303 http://dx.doi.org/10.1016/j.celrep.2022.111895 |