PD-1(high)CXCR5(–)CD4(+) peripheral helper T cells promote CXCR3(+) plasmablasts in human acute viral infection

T cell-B cell interaction is the key immune response to protect the host from severe viral infection. However, how T cells support B cells to exert protective humoral immunity in humans is not well understood. Here, we use COVID-19 as a model of acute viral infections and analyze CD4(+) T cell subse...

Descripción completa

Detalles Bibliográficos
Autores principales: Asashima, Hiromitsu, Mohanty, Subhasis, Comi, Michela, Ruff, William E., Hoehn, Kenneth B., Wong, Patrick, Klein, Jon, Lucas, Carolina, Cohen, Inessa, Coffey, Sarah, Lele, Nikhil, Greta, Leissa, Raddassi, Khadir, Chaudhary, Omkar, Unterman, Avraham, Emu, Brinda, Kleinstein, Steven H., Montgomery, Ruth R., Iwasaki, Akiko, Dela Cruz, Charles S., Kaminski, Naftali, Shaw, Albert C., Hafler, David A., Sumida, Tomokazu S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2023
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806868/
https://www.ncbi.nlm.nih.gov/pubmed/36596303
http://dx.doi.org/10.1016/j.celrep.2022.111895

Ejemplares similares

Ejemplares similares