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Mediation of PKM2-dependent glycolytic and non-glycolytic pathways by ENO2 in head and neck cancer development

BACKGROUND: Enolase 2 (ENO2) is a crucial glycolytic enzyme in cancer metabolic process and acts as a “moonlighting” protein to play various functions in diverse cellular processes unrelated to glycolysis. ENO2 is highly expressed in head and neck squamous cell carcinoma (HNSCC) tissues relative to...

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Detalles Bibliográficos
Autores principales: Gao, Lixia, Yang, Fan, Tang, Dianyong, Xu, Zhigang, Tang, Yan, Yang, Donglin, Sun, Deping, Chen, Zhongzhu, Teng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9806895/
https://www.ncbi.nlm.nih.gov/pubmed/36588153
http://dx.doi.org/10.1186/s13046-022-02574-0