In vivo partial cellular reprogramming enhances liver plasticity and regeneration

Mammals have limited regenerative capacity, whereas some vertebrates, like fish and salamanders, are able to regenerate their organs efficiently. The regeneration in these species depends on cell dedifferentiation followed by proliferation. We generate a mouse model that enables the inducible expres...

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Detalles Bibliográficos
Autores principales: Hishida, Tomoaki, Yamamoto, Mako, Hishida-Nozaki, Yuriko, Shao, Changwei, Huang, Ling, Wang, Chao, Shojima, Kensaku, Xue, Yuan, Hang, Yuqing, Shokhirev, Maxim, Memczak, Sebastian, Sahu, Sanjeeb Kumar, Hatanaka, Fumiyuki, Ros, Ruben Rabadan, Maxwell, Matthew B., Chavez, Jasmine, Shao, Yanjiao, Liao, Hsin-Kai, Martinez-Redondo, Paloma, Guillen-Guillen, Isabel, Hernandez-Benitez, Reyna, Esteban, Concepcion Rodriguez, Qu, Jing, Holmes, Michael C., Yi, Fei, Hickey, Raymond D., Garcia, Pedro Guillen, Delicado, Estrella Nuñez, Castells, Antoni, Campistol, Josep M., Yu, Yang, Hargreaves, Diana C., Asai, Akihiro, Reddy, Pradeep, Liu, Guang-Hui, Belmonte, Juan Carlos Izpisua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807246/
https://www.ncbi.nlm.nih.gov/pubmed/35476977
http://dx.doi.org/10.1016/j.celrep.2022.110730

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