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Ceramide Synthase 6 Mediates Triple-Negative Breast Cancer Response to Chemotherapy Through RhoA- and EGFR-Mediated Signaling Pathways

PURPOSE: Limited treatment options and lack of treatment sensitivity biomarkers make the clinical management of triple-negative breast cancer (TNBC) challenging. Ceramide synthase 6 (CERS6) generates ceramides, which are key intermediates in sphingolipid biosynthesis and play important roles in canc...

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Detalles Bibliográficos
Autores principales:	Chen, Hui, He, Bin, Ke, Feng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Breast Cancer Society 2022
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807320/ https://www.ncbi.nlm.nih.gov/pubmed/36479603 http://dx.doi.org/10.4048/jbc.2022.25.e47

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