Genomic evidence of SARS-CoV-2 reinfection cases in southern Brazil

Cases of reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported worldwide. We investigated reinfection cases in a set of more than 30,000 samples, and the SARS-CoV-2 genomes from selected samples from four patients with at least two positive diagnoses with a...

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Detalles Bibliográficos
Autores principales: Varela, Ana Paula Muterle, Sant’Anna, Fernando Hayashi, dos Santos, Aniúsca Vieira, Prichula, Janira, Comerlato, Juliana, dos Santos, Giovana Tavares, Wendland, Eliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2023
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807423/
https://www.ncbi.nlm.nih.gov/pubmed/36593369
http://dx.doi.org/10.1007/s00705-022-05648-8
Descripción
Sumario:Cases of reinfection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported worldwide. We investigated reinfection cases in a set of more than 30,000 samples, and the SARS-CoV-2 genomes from selected samples from four patients with at least two positive diagnoses with an interval ≥ 45 days between tests were sequenced and analyzed. Comparative genomic and phylogenetic analysis confirmed three reinfection cases and suggested that the fourth one was caused by a virus of the same lineage. Viral sequencing is crucial for understanding the natural course of reinfections and for planning public health strategies for management of COVID-19. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s00705-022-05648-8.

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