Cargando…
Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report
Rapid and reliable identification of targetable driver mutations in patients with advanced stage lung cancer is essential. Adequate amount of tumor tissue biopsies (i.e., genomic biopsies) are required to successfully analyze the gene panel. In the present case, we performed three pleural fluid inve...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Australia, Ltd
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807439/ https://www.ncbi.nlm.nih.gov/pubmed/36404408 http://dx.doi.org/10.1111/1759-7714.14738 |
_version_ | 1784862719213568000 |
---|---|
author | Kunimasa, Kei Inoue, Takako Kai, Yugo Kanzaki, Ryu Kawagishi, Sachi Yoshida, Ken‐ichi Honma, Keiichiro Tamiya, Motohiro Kawamura, Takahisa Nishino, Kazumi |
author_facet | Kunimasa, Kei Inoue, Takako Kai, Yugo Kanzaki, Ryu Kawagishi, Sachi Yoshida, Ken‐ichi Honma, Keiichiro Tamiya, Motohiro Kawamura, Takahisa Nishino, Kazumi |
author_sort | Kunimasa, Kei |
collection | PubMed |
description | Rapid and reliable identification of targetable driver mutations in patients with advanced stage lung cancer is essential. Adequate amount of tumor tissue biopsies (i.e., genomic biopsies) are required to successfully analyze the gene panel. In the present case, we performed three pleural fluid investigations, including transbronchial biopsy of the primary tumor, transesophageal endoscopic ultrasound‐guided fine needle aspiration (EUS‐FNA) of lymph node metastasis, and thoracoscopic biopsy of the pleural seeding sites. Among the three investigations, thoracoscopic biopsy alone successfully obtained a sufficient amount of tissue. Thus, it is important to determine the technique and site of biopsy, as multiple biopsies are not only burdensome to the patient, but also lead to significant delays in therapy induction. |
format | Online Article Text |
id | pubmed-9807439 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | John Wiley & Sons Australia, Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-98074392023-01-04 Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report Kunimasa, Kei Inoue, Takako Kai, Yugo Kanzaki, Ryu Kawagishi, Sachi Yoshida, Ken‐ichi Honma, Keiichiro Tamiya, Motohiro Kawamura, Takahisa Nishino, Kazumi Thorac Cancer Case Reports Rapid and reliable identification of targetable driver mutations in patients with advanced stage lung cancer is essential. Adequate amount of tumor tissue biopsies (i.e., genomic biopsies) are required to successfully analyze the gene panel. In the present case, we performed three pleural fluid investigations, including transbronchial biopsy of the primary tumor, transesophageal endoscopic ultrasound‐guided fine needle aspiration (EUS‐FNA) of lymph node metastasis, and thoracoscopic biopsy of the pleural seeding sites. Among the three investigations, thoracoscopic biopsy alone successfully obtained a sufficient amount of tissue. Thus, it is important to determine the technique and site of biopsy, as multiple biopsies are not only burdensome to the patient, but also lead to significant delays in therapy induction. John Wiley & Sons Australia, Ltd 2022-11-20 /pmc/articles/PMC9807439/ /pubmed/36404408 http://dx.doi.org/10.1111/1759-7714.14738 Text en © 2022 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes. |
spellingShingle | Case Reports Kunimasa, Kei Inoue, Takako Kai, Yugo Kanzaki, Ryu Kawagishi, Sachi Yoshida, Ken‐ichi Honma, Keiichiro Tamiya, Motohiro Kawamura, Takahisa Nishino, Kazumi Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report |
title | Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report |
title_full | Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report |
title_fullStr | Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report |
title_full_unstemmed | Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report |
title_short | Rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: A case report |
title_sort | rapid and reliable collection of tumor tissue for successful gene panel in a patient with advanced stage lung cancer: a case report |
topic | Case Reports |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807439/ https://www.ncbi.nlm.nih.gov/pubmed/36404408 http://dx.doi.org/10.1111/1759-7714.14738 |
work_keys_str_mv | AT kunimasakei rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport AT inouetakako rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport AT kaiyugo rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport AT kanzakiryu rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport AT kawagishisachi rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport AT yoshidakenichi rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport AT honmakeiichiro rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport AT tamiyamotohiro rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport AT kawamuratakahisa rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport AT nishinokazumi rapidandreliablecollectionoftumortissueforsuccessfulgenepanelinapatientwithadvancedstagelungcanceracasereport |