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A single‐center study of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors

OBJECTIVE: To study the feasibility, safety, and efficacy of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors, and summarize the treatment experiences and surgical skills. METHODS: A single‐center retrospective analysis of 37 patients with pediatric mediastinal neuro...

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Autores principales: Zhang, Qiangye, Zhou, Tingting, Hou, Peimin, Mu, Weijing, Wang, Dongming, Fang, Jun, Li, Aiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807445/
https://www.ncbi.nlm.nih.gov/pubmed/36351570
http://dx.doi.org/10.1111/1759-7714.14708
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author Zhang, Qiangye
Zhou, Tingting
Hou, Peimin
Mu, Weijing
Wang, Dongming
Fang, Jun
Li, Aiwu
author_facet Zhang, Qiangye
Zhou, Tingting
Hou, Peimin
Mu, Weijing
Wang, Dongming
Fang, Jun
Li, Aiwu
author_sort Zhang, Qiangye
collection PubMed
description OBJECTIVE: To study the feasibility, safety, and efficacy of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors, and summarize the treatment experiences and surgical skills. METHODS: A single‐center retrospective analysis of 37 patients with pediatric mediastinal neurogenic tumors was conducted. Clinical charactersistics and postoperative complications were all analyzed. RESULTS: All the operations were successfully completed. There was no statistically significant difference in tumor diameter between the two groups (p > 0.05). The open surgery group had an average operation time of 96.5 ± 32.38 min, while the thoracoscopic surgery group had an average operation time of 78.3 ± 24.51 min (p < 0.05). The thoracoscopic surgery group had significantly lower intraoperative blood loss than the open surgery group (p < 0.05). In addition, the duration of the postoperative thoracic drainage tube was 5.43 ± 0.76 days in the open surgery group, which was longer than the 2.38 ± 0.87 days in the thoracoscopic surgery group (p < 0.05). Furthermore, the postoperative length of hospital stay was an average of 10.23 ± 1.43 days for the open surgery group, longer than for the thoracoscopic surgery group (4.36 ± 0.87 days) (p < 0.05). CONCLUSIONS: Thoracoscopic surgery has several advantages in the treatment of pediatric mediastinal neurogenic tumors and is worthy of clinical popularization and application. For giant mediastinal malignant neurogenic tumors, puncture biopsy and adjuvant chemotherapy can be performed before surgery to lessen the tumor volume and enlarge the operation space, which would reduce bleeding and complications.
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spelling pubmed-98074452023-01-04 A single‐center study of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors Zhang, Qiangye Zhou, Tingting Hou, Peimin Mu, Weijing Wang, Dongming Fang, Jun Li, Aiwu Thorac Cancer Original Articles OBJECTIVE: To study the feasibility, safety, and efficacy of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors, and summarize the treatment experiences and surgical skills. METHODS: A single‐center retrospective analysis of 37 patients with pediatric mediastinal neurogenic tumors was conducted. Clinical charactersistics and postoperative complications were all analyzed. RESULTS: All the operations were successfully completed. There was no statistically significant difference in tumor diameter between the two groups (p > 0.05). The open surgery group had an average operation time of 96.5 ± 32.38 min, while the thoracoscopic surgery group had an average operation time of 78.3 ± 24.51 min (p < 0.05). The thoracoscopic surgery group had significantly lower intraoperative blood loss than the open surgery group (p < 0.05). In addition, the duration of the postoperative thoracic drainage tube was 5.43 ± 0.76 days in the open surgery group, which was longer than the 2.38 ± 0.87 days in the thoracoscopic surgery group (p < 0.05). Furthermore, the postoperative length of hospital stay was an average of 10.23 ± 1.43 days for the open surgery group, longer than for the thoracoscopic surgery group (4.36 ± 0.87 days) (p < 0.05). CONCLUSIONS: Thoracoscopic surgery has several advantages in the treatment of pediatric mediastinal neurogenic tumors and is worthy of clinical popularization and application. For giant mediastinal malignant neurogenic tumors, puncture biopsy and adjuvant chemotherapy can be performed before surgery to lessen the tumor volume and enlarge the operation space, which would reduce bleeding and complications. John Wiley & Sons Australia, Ltd 2022-11-09 /pmc/articles/PMC9807445/ /pubmed/36351570 http://dx.doi.org/10.1111/1759-7714.14708 Text en © 2022 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Zhang, Qiangye
Zhou, Tingting
Hou, Peimin
Mu, Weijing
Wang, Dongming
Fang, Jun
Li, Aiwu
A single‐center study of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors
title A single‐center study of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors
title_full A single‐center study of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors
title_fullStr A single‐center study of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors
title_full_unstemmed A single‐center study of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors
title_short A single‐center study of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors
title_sort single‐center study of thoracoscopic surgery in the treatment of pediatric mediastinal neurogenic tumors
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807445/
https://www.ncbi.nlm.nih.gov/pubmed/36351570
http://dx.doi.org/10.1111/1759-7714.14708
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