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Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807471/ https://www.ncbi.nlm.nih.gov/pubmed/36403175 http://dx.doi.org/10.1007/s00401-022-02518-0 |
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author | Gottardo, Nicholas G. |
author_facet | Gottardo, Nicholas G. |
author_sort | Gottardo, Nicholas G. |
collection | PubMed |
description | |
format | Online Article Text |
id | pubmed-9807471 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-98074712023-01-04 Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials Gottardo, Nicholas G. Acta Neuropathol Correspondence Springer Berlin Heidelberg 2022-11-20 2023 /pmc/articles/PMC9807471/ /pubmed/36403175 http://dx.doi.org/10.1007/s00401-022-02518-0 Text en © Crown 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Correspondence Gottardo, Nicholas G. Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials |
title | Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials |
title_full | Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials |
title_fullStr | Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials |
title_full_unstemmed | Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials |
title_short | Genetic alterations of TP53 and OTX2 indicate increased risk of relapse in WNT medulloblastomas: “it’s a numbers game”—implications for WNT medulloblastoma dose-reduction clinical trials |
title_sort | genetic alterations of tp53 and otx2 indicate increased risk of relapse in wnt medulloblastomas: “it’s a numbers game”—implications for wnt medulloblastoma dose-reduction clinical trials |
topic | Correspondence |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807471/ https://www.ncbi.nlm.nih.gov/pubmed/36403175 http://dx.doi.org/10.1007/s00401-022-02518-0 |
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