Nucleic acid–triggered tumoral immunity propagates pH‐selective therapeutic antibodies through tumor‐driven epitope spreading

Important roles of humoral tumor immunity are often pointed out; however, precise profiles of dominant antigens and developmental mechanisms remain elusive. We systematically investigated the humoral antigens of dominant intratumor immunoglobulin clones found in human cancers. We found that approxim...

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Detalles Bibliográficos
Autores principales: Furuya, Genta, Katoh, Hiroto, Atsumi, Shinichiro, Hashimoto, Itaru, Komura, Daisuke, Hatanaka, Ryo, Senga, Shogo, Hayashi, Shuto, Akita, Shoji, Matsumura, Hirofumi, Miura, Akihiro, Mita, Hideaki, Nakakido, Makoto, Nagatoishi, Satoru, Sugiyama, Akira, Suzuki, Ryohei, Konishi, Hiroki, Yamamoto, Asami, Abe, Hiroyuki, Hiraoka, Nobuyoshi, Aoki, Kazunori, Kato, Yasumasa, Seto, Yasuyuki, Yoshimura, Chihoko, Miyadera, Kazutaka, Tsumoto, Kouhei, Ushiku, Tetsuo, Ishikawa, Shumpei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807517/
https://www.ncbi.nlm.nih.gov/pubmed/36136061
http://dx.doi.org/10.1111/cas.15596

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