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ROS inhibits RORα degradation by decreasing its arginine methylation in liver cancer

Retinoic acid receptor–related orphan receptor α (RORα) is a transcription factor involved in nuclear gene expression and a known tumor suppressor. RORα was the first identified substrate of lysine methylation–dependent degradation. However, the mechanisms of other post‐translational modifications (...

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Detalles Bibliográficos
Autores principales: Im, Hyuntae, Baek, Hee‐ji, Yang, Eunbi, Kim, Kyeongkyu, Oh, Se Kyu, Lee, Jung‐Shin, Kim, Hyunkyung, Lee, Ji Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807526/
https://www.ncbi.nlm.nih.gov/pubmed/36114756
http://dx.doi.org/10.1111/cas.15595