RNA methyltransferase NSun2 deficiency promotes neurodegeneration through epitranscriptomic regulation of tau phosphorylation

Epitranscriptomic regulation adds a layer of post-transcriptional control to brain function during development and adulthood. The identification of RNA-modifying enzymes has opened the possibility of investigating the role epitranscriptomic changes play in the disease process. NOP2/Sun RNA methyltra...

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Detalles Bibliográficos
Autores principales: Kim, Yoon A., Siddiqui, Tohid, Blaze, Jennifer, Cosacak, Mehmet Ilyas, Winters, Tristan, Kumar, Atul, Tein, Ellen, Sproul, Andrew A., Teich, Andrew F., Bartolini, Francesca, Akbarian, Schahram, Kizil, Caghan, Hargus, Gunnar, Santa-Maria, Ismael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807547/
https://www.ncbi.nlm.nih.gov/pubmed/36357715
http://dx.doi.org/10.1007/s00401-022-02511-7

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