Expanded genetic testing of GIST patients identifies high proportion of non-syndromic patients with germline alterations

Traditional genetic testing for patients with gastrointestinal stromal tumors (GISTs) focus on those with syndromic features. To assess whether expanded genetic testing of GIST patients could identify hereditary cancer predisposition, we analyzed matched tumor-germline sequencing results from 103 pa...

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Detalles Bibliográficos
Autores principales: Mandelker, Diana, Marra, Antonio, Mehta, Nikita, Selenica, Pier, Yelskaya, Zarina, Yang, Ciyu, Somar, Joshua, Mehine, Miika, Misyura, Maksym, Basturk, Olca, Latham, Alicia, Carlo, Maria, Walsh, Michael, Stadler, Zsofia K., Offit, Kenneth, Bandlamudi, Chaitanya, Hameed, Meera, Chi, Ping, Reis-Filho, Jorge S., Ceyhan-Birsoy, Ozge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807588/
https://www.ncbi.nlm.nih.gov/pubmed/36593350
http://dx.doi.org/10.1038/s41698-022-00342-z

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