SARS-CoV-2 vaccine excipients polyethylene glycol and trometamol do not induce mast cell degranulation, in an in vitro model for non-IgE-mediated hypersensitivity

The development of vaccines against SARS-CoV2 brought about several challenges, including the management of hypersensitivity reactions to these formulations. The search for underlying mechanisms involved in these adverse events initially focused on excipients which may trigger mast cell activation r...

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Detalles Bibliográficos
Autores principales: Quan, Paola Leonor, Ollé, Laia, Sabaté-Brescó, Marina, Guo, Yanru, Muñoz-Cano, Rosa, Wagner, Annette, Gastaminza, Gabriel, Martín, Margarita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Allergy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807604/
https://www.ncbi.nlm.nih.gov/pubmed/36606064
http://dx.doi.org/10.3389/falgy.2022.1046545

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