AKT1 regulates UHRF1 protein stability and promotes the resistance to abiraterone in prostate cancer

Oncogenic activation of PI3K/AKT signaling pathway, together with epigenetic aberrations are the characters of castration-resistant prostate cancer (CRPC). UHRF1 as a key epigenetic regulator, plays a critical role in prostate cancer (PCa) development, and its expression is positively correlated wit...

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Detalles Bibliográficos
Autores principales: Fu, Yongming, Cao, Tuoyu, Zou, Xiaorui, Ye, Yubing, Liu, Youhong, Peng, Yuchong, Deng, Tanggang, Yin, Linglong, Li, Xiong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807647/
https://www.ncbi.nlm.nih.gov/pubmed/36593255
http://dx.doi.org/10.1038/s41389-022-00446-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9807647/
https://www.ncbi.nlm.nih.gov/pubmed/36593255
http://dx.doi.org/10.1038/s41389-022-00446-y

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