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A decline of protective apolipoprotein J and complement factor H concomitant with increase in C5a 3 months after cardiac surgery—Evidence of long-term complement perturbations

BACKGROUND: Heart surgery results in complement activation with the potential for collateral end-organ damage, especially if the protective elements (complement factor H, Apolipoprotein J) are inadequate. Here, we have investigated if peri-operative stress results in an imbalance between complement...

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Detalles Bibliográficos
Autores principales: Laudanski, Krzysztof, Liu, Da, Gullipalli, Damodar, Song, Wen-Chao, Okeke, Tony, Szeto, Wilson Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808065/
https://www.ncbi.nlm.nih.gov/pubmed/36606279
http://dx.doi.org/10.3389/fcvm.2022.983617