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Lumbar spine surgery reduces postoperative opioid use in the veteran population

BACKGROUND: The United States has been facing a worsening opioid epidemic over the past two decades. The veteran population represents a large and vulnerable group with a higher burden of mental health comorbidities. The purpose of this study was to analyze the impact of lumbar spine surgery on post...

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Autores principales: Rezaii, Paymon G., Cole, Matthew W., Clark, Sean C., Lee, Olivia C., Cyriac, Mathew, Dumont, Aaron S., Sherman, William F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808105/
https://www.ncbi.nlm.nih.gov/pubmed/36605994
http://dx.doi.org/10.21037/jss-22-50
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author Rezaii, Paymon G.
Cole, Matthew W.
Clark, Sean C.
Lee, Olivia C.
Cyriac, Mathew
Dumont, Aaron S.
Sherman, William F.
author_facet Rezaii, Paymon G.
Cole, Matthew W.
Clark, Sean C.
Lee, Olivia C.
Cyriac, Mathew
Dumont, Aaron S.
Sherman, William F.
author_sort Rezaii, Paymon G.
collection PubMed
description BACKGROUND: The United States has been facing a worsening opioid epidemic over the past two decades. The veteran population represents a large and vulnerable group with a higher burden of mental health comorbidities. The purpose of this study was to analyze the impact of lumbar spine surgery on postoperative opioid usage in the United States veteran population. METHODS: A retrospective cohort study was conducted using the Veterans Affairs Informatics and Computing Infrastructure database. Patients who underwent lumbar spine surgery were stratified into three groups by their preoperative opioid claims within 365 days of surgery. Postoperative cumulative morphine milligram equivalents (MME) were tracked for each group and the paired Wilcoxon signed rank test was used to compare cumulative preoperative MME (days −365–0) to cumulative postoperative MME (days 91–455). RESULTS: At one year, 30.6% of patients in the high preoperative opioid group and 73.1% of patients in the low preoperative opioid group were no longer using opioids. In the opioid naive cohort, 10.0% of patients were still using opioids at one year. Among all patients, median cumulative postoperative MME was significantly less than median cumulative preoperative MME (P<0.001). High preoperative opioid usage of more than 3 claims was most significantly associated with continued postoperative opioid usage (odds ratio 12.55, P<0.001). From 2010 to 2020 the proportion of patients with preoperative opioid claims decreased (58.8% to 34.8%). CONCLUSIONS: In the veteran population, lumbar spine surgery was effective in getting 50% of patients who were on opioids preoperatively to discontinue opioids postoperatively. Even minimal exposure to opioids preoperatively resulted in a 2.69-time increase in risk of being on opioids at one year versus opioid naive patients. This study affirms that despite being a high-risk population, the veteran population has a similar response to lumbar spine surgery as the general population in regards to opioid dependence.
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spelling pubmed-98081052023-01-04 Lumbar spine surgery reduces postoperative opioid use in the veteran population Rezaii, Paymon G. Cole, Matthew W. Clark, Sean C. Lee, Olivia C. Cyriac, Mathew Dumont, Aaron S. Sherman, William F. J Spine Surg Original Article BACKGROUND: The United States has been facing a worsening opioid epidemic over the past two decades. The veteran population represents a large and vulnerable group with a higher burden of mental health comorbidities. The purpose of this study was to analyze the impact of lumbar spine surgery on postoperative opioid usage in the United States veteran population. METHODS: A retrospective cohort study was conducted using the Veterans Affairs Informatics and Computing Infrastructure database. Patients who underwent lumbar spine surgery were stratified into three groups by their preoperative opioid claims within 365 days of surgery. Postoperative cumulative morphine milligram equivalents (MME) were tracked for each group and the paired Wilcoxon signed rank test was used to compare cumulative preoperative MME (days −365–0) to cumulative postoperative MME (days 91–455). RESULTS: At one year, 30.6% of patients in the high preoperative opioid group and 73.1% of patients in the low preoperative opioid group were no longer using opioids. In the opioid naive cohort, 10.0% of patients were still using opioids at one year. Among all patients, median cumulative postoperative MME was significantly less than median cumulative preoperative MME (P<0.001). High preoperative opioid usage of more than 3 claims was most significantly associated with continued postoperative opioid usage (odds ratio 12.55, P<0.001). From 2010 to 2020 the proportion of patients with preoperative opioid claims decreased (58.8% to 34.8%). CONCLUSIONS: In the veteran population, lumbar spine surgery was effective in getting 50% of patients who were on opioids preoperatively to discontinue opioids postoperatively. Even minimal exposure to opioids preoperatively resulted in a 2.69-time increase in risk of being on opioids at one year versus opioid naive patients. This study affirms that despite being a high-risk population, the veteran population has a similar response to lumbar spine surgery as the general population in regards to opioid dependence. AME Publishing Company 2022-12 /pmc/articles/PMC9808105/ /pubmed/36605994 http://dx.doi.org/10.21037/jss-22-50 Text en 2022 Journal of Spine Surgery. All rights reserved. https://creativecommons.org/licenses/by-nc-nd/4.0/Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) .
spellingShingle Original Article
Rezaii, Paymon G.
Cole, Matthew W.
Clark, Sean C.
Lee, Olivia C.
Cyriac, Mathew
Dumont, Aaron S.
Sherman, William F.
Lumbar spine surgery reduces postoperative opioid use in the veteran population
title Lumbar spine surgery reduces postoperative opioid use in the veteran population
title_full Lumbar spine surgery reduces postoperative opioid use in the veteran population
title_fullStr Lumbar spine surgery reduces postoperative opioid use in the veteran population
title_full_unstemmed Lumbar spine surgery reduces postoperative opioid use in the veteran population
title_short Lumbar spine surgery reduces postoperative opioid use in the veteran population
title_sort lumbar spine surgery reduces postoperative opioid use in the veteran population
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808105/
https://www.ncbi.nlm.nih.gov/pubmed/36605994
http://dx.doi.org/10.21037/jss-22-50
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