Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022

We report a ceftriaxone-resistant, multidrug-resistant urogenital gonorrhoea case in a heterosexual woman in France, June 2022. The woman was successfully treated with azithromycin 2 g. She had unprotected sex with her regular partner, who developed urethritis following travel to Vietnam and Switzer...

Descripción completa

Detalles Bibliográficos
Autores principales: Berçot, Béatrice, Caméléna, François, Mérimèche, Manel, Jacobsson, Susanne, Sbaa, Ghalia, Mainardis, Mary, Valin, Cyrille, Molina, Jean-Michel, Bébéar, Cécile, Chazelle, Emilie, Lot, Florence, Golparian, Daniel, Unemo, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808317/
https://www.ncbi.nlm.nih.gov/pubmed/36695466
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.50.2200899
Descripción
Sumario:We report a ceftriaxone-resistant, multidrug-resistant urogenital gonorrhoea case in a heterosexual woman in France, June 2022. The woman was successfully treated with azithromycin 2 g. She had unprotected sex with her regular partner, who developed urethritis following travel to Vietnam and Switzerland. Whole genome sequencing of the gonococcal isolate (F92) identified MLST ST1901, NG-STAR CC-199, and the novel mosaic penA-237.001, which caused ceftriaxone resistance. penA-237.001 is 98.7% identical to penA-60.001, reported in various ceftriaxone-resistant strains, including the internationally spreading FC428 clone.

Ejemplares similares