Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022

We report a ceftriaxone-resistant, multidrug-resistant urogenital gonorrhoea case in a heterosexual woman in France, June 2022. The woman was successfully treated with azithromycin 2 g. She had unprotected sex with her regular partner, who developed urethritis following travel to Vietnam and Switzer...

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Autores principales: Berçot, Béatrice, Caméléna, François, Mérimèche, Manel, Jacobsson, Susanne, Sbaa, Ghalia, Mainardis, Mary, Valin, Cyrille, Molina, Jean-Michel, Bébéar, Cécile, Chazelle, Emilie, Lot, Florence, Golparian, Daniel, Unemo, Magnus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808317/
https://www.ncbi.nlm.nih.gov/pubmed/36695466
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.50.2200899
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author Berçot, Béatrice
Caméléna, François
Mérimèche, Manel
Jacobsson, Susanne
Sbaa, Ghalia
Mainardis, Mary
Valin, Cyrille
Molina, Jean-Michel
Bébéar, Cécile
Chazelle, Emilie
Lot, Florence
Golparian, Daniel
Unemo, Magnus
author_facet Berçot, Béatrice
Caméléna, François
Mérimèche, Manel
Jacobsson, Susanne
Sbaa, Ghalia
Mainardis, Mary
Valin, Cyrille
Molina, Jean-Michel
Bébéar, Cécile
Chazelle, Emilie
Lot, Florence
Golparian, Daniel
Unemo, Magnus
author_sort Berçot, Béatrice
collection PubMed
description We report a ceftriaxone-resistant, multidrug-resistant urogenital gonorrhoea case in a heterosexual woman in France, June 2022. The woman was successfully treated with azithromycin 2 g. She had unprotected sex with her regular partner, who developed urethritis following travel to Vietnam and Switzerland. Whole genome sequencing of the gonococcal isolate (F92) identified MLST ST1901, NG-STAR CC-199, and the novel mosaic penA-237.001, which caused ceftriaxone resistance. penA-237.001 is 98.7% identical to penA-60.001, reported in various ceftriaxone-resistant strains, including the internationally spreading FC428 clone.
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spelling pubmed-98083172023-01-04 Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022 Berçot, Béatrice Caméléna, François Mérimèche, Manel Jacobsson, Susanne Sbaa, Ghalia Mainardis, Mary Valin, Cyrille Molina, Jean-Michel Bébéar, Cécile Chazelle, Emilie Lot, Florence Golparian, Daniel Unemo, Magnus Euro Surveill Rapid Communication We report a ceftriaxone-resistant, multidrug-resistant urogenital gonorrhoea case in a heterosexual woman in France, June 2022. The woman was successfully treated with azithromycin 2 g. She had unprotected sex with her regular partner, who developed urethritis following travel to Vietnam and Switzerland. Whole genome sequencing of the gonococcal isolate (F92) identified MLST ST1901, NG-STAR CC-199, and the novel mosaic penA-237.001, which caused ceftriaxone resistance. penA-237.001 is 98.7% identical to penA-60.001, reported in various ceftriaxone-resistant strains, including the internationally spreading FC428 clone. European Centre for Disease Prevention and Control (ECDC) 2022-12-15 /pmc/articles/PMC9808317/ /pubmed/36695466 http://dx.doi.org/10.2807/1560-7917.ES.2022.27.50.2200899 Text en This article is copyright of the authors or their affiliated institutions, 2022. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution (CC BY 4.0) Licence. You may share and adapt the material, but must give appropriate credit to the source, provide a link to the licence, and indicate if changes were made.
spellingShingle Rapid Communication
Berçot, Béatrice
Caméléna, François
Mérimèche, Manel
Jacobsson, Susanne
Sbaa, Ghalia
Mainardis, Mary
Valin, Cyrille
Molina, Jean-Michel
Bébéar, Cécile
Chazelle, Emilie
Lot, Florence
Golparian, Daniel
Unemo, Magnus
Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022
title Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022
title_full Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022
title_fullStr Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022
title_full_unstemmed Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022
title_short Ceftriaxone-resistant, multidrug-resistant Neisseria gonorrhoeae with a novel mosaic penA-237.001 gene, France, June 2022
title_sort ceftriaxone-resistant, multidrug-resistant neisseria gonorrhoeae with a novel mosaic pena-237.001 gene, france, june 2022
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808317/
https://www.ncbi.nlm.nih.gov/pubmed/36695466
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.50.2200899
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