Increase in NDM-1 and NDM-1/OXA-48-producing Klebsiella pneumoniae in Germany associated with the war in Ukraine, 2022

In 2022, German surveillance systems observed rapidly increasing numbers of NDM-1- and NDM-1/OXA-48-producing Klebsiella pneumoniae, which may in part reflect recurring pre-pandemic trends. Among these cases, however, a presence in Ukraine before diagnosis was frequently reported. Whole genome seque...

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Detalles Bibliográficos
Autores principales: Sandfort, Mirco, Hans, Jörg B, Fischer, Martin A, Reichert, Felix, Cremanns, Martina, Eisfeld, Jessica, Pfeifer, Yvonne, Heck, Annika, Eckmanns, Tim, Werner, Guido, Gatermann, Sören, Haller, Sebastian, Pfennigwerth, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Centre for Disease Prevention and Control (ECDC) 2022
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808319/
https://www.ncbi.nlm.nih.gov/pubmed/36695468
http://dx.doi.org/10.2807/1560-7917.ES.2022.27.50.2200926
Descripción
Sumario:In 2022, German surveillance systems observed rapidly increasing numbers of NDM-1- and NDM-1/OXA-48-producing Klebsiella pneumoniae, which may in part reflect recurring pre-pandemic trends. Among these cases, however, a presence in Ukraine before diagnosis was frequently reported. Whole genome sequencing of 200 isolates showed a high prevalence of sequence types ST147, ST307, ST395 and ST23, including clusters corresponding to clonal dissemination and suggesting onward transmission in Germany. Screening and isolation of patients from Ukraine may help avoid onward transmission.

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