Extracellular Galectin 4 Drives Immune Evasion and Promotes T-cell Apoptosis in Pancreatic Cancer

Pancreatic ductal adenocarcinoma (PDAC) is characterized by rich deposits of extracellular matrix (ECM), affecting the pathophysiology of the disease. Here, we identified galectin 4 (gal 4) as a cancer cell–produced protein that was deposited into the ECM of PDAC tumors and detected high-circulating...

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Detalles Bibliográficos
Autores principales: Lidström, Tommy, Cumming, Joshua, Gaur, Rahul, Frängsmyr, Lars, Pateras, Ioannis S., Mickert, Matthias J., Franklin, Oskar, Forsell, Mattias N.E., Arnberg, Niklas, Dongre, Mitesh, Patthey, Cedric, Öhlund, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for Cancer Research 2023
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808371/
https://www.ncbi.nlm.nih.gov/pubmed/36478037
http://dx.doi.org/10.1158/2326-6066.CIR-21-1088

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