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Canonical and uncanonical pathogenic germline variants in colorectal cancer patients by next-generation sequencing in a European referral center

BACKGROUND: Despite increasing use of next-generation sequencing (NGS), data concerning the gain in germline pathogenic variants (PVs) remain scanty, especially with respect to uncanonical ones. We aimed to verify the impact of different cancer predisposition genes (CPGs) on colorectal cancer (CRC)...

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Detalles Bibliográficos
Autores principales:	Poliani, L., Greco, L., Barile, M., Dal Buono, A., Bianchi, P., Basso, G., Giatti, V., Genuardi, M., Malesci, A., Laghi, L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808471/ https://www.ncbi.nlm.nih.gov/pubmed/36356413 http://dx.doi.org/10.1016/j.esmoop.2022.100607

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