Deep sequencing analysis of acute conjunctivitis in Burkina Faso, Africa

BACKGROUND: Seasonal and epidemic conjunctivitis (pink eye) infections are highly contagious and impose a significant economic burden worldwide. Long-term visual impairment can occur. METHODS: This study used metagenomic deep sequencing to evaluate pathogens causing acute infectious conjunctivitis i...

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Autores principales: Bountogo, Mamadou, Sié, Ali, Coulibaly, Boubacar, Ruder, Kevin, Chen, Cindi, Zhong, Lina, Colby, Emily, Lebas, Elodie, Deiner, Michael, Hinterwirth, Armin, Lietman, Thomas M, Seitzman, Gerami D, Doan, Thuy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808514/
https://www.ncbi.nlm.nih.gov/pubmed/35076074
http://dx.doi.org/10.1093/inthealth/ihac001
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author Bountogo, Mamadou
Sié, Ali
Coulibaly, Boubacar
Ruder, Kevin
Chen, Cindi
Zhong, Lina
Colby, Emily
Lebas, Elodie
Deiner, Michael
Hinterwirth, Armin
Lietman, Thomas M
Seitzman, Gerami D
Doan, Thuy
author_facet Bountogo, Mamadou
Sié, Ali
Coulibaly, Boubacar
Ruder, Kevin
Chen, Cindi
Zhong, Lina
Colby, Emily
Lebas, Elodie
Deiner, Michael
Hinterwirth, Armin
Lietman, Thomas M
Seitzman, Gerami D
Doan, Thuy
author_sort Bountogo, Mamadou
collection PubMed
description BACKGROUND: Seasonal and epidemic conjunctivitis (pink eye) infections are highly contagious and impose a significant economic burden worldwide. Long-term visual impairment can occur. METHODS: This study used metagenomic deep sequencing to evaluate pathogens causing acute infectious conjunctivitis in Burkina Faso. RESULTS: We found that pathogens causing conjunctivitis in Burkina Faso are diverse, with human adenoviruses responsible for a small fraction of the samples tested. CONCLUSIONS: These results are unexpected and suggest the importance of regional surveillance.
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spelling pubmed-98085142023-01-04 Deep sequencing analysis of acute conjunctivitis in Burkina Faso, Africa Bountogo, Mamadou Sié, Ali Coulibaly, Boubacar Ruder, Kevin Chen, Cindi Zhong, Lina Colby, Emily Lebas, Elodie Deiner, Michael Hinterwirth, Armin Lietman, Thomas M Seitzman, Gerami D Doan, Thuy Int Health Short Communication BACKGROUND: Seasonal and epidemic conjunctivitis (pink eye) infections are highly contagious and impose a significant economic burden worldwide. Long-term visual impairment can occur. METHODS: This study used metagenomic deep sequencing to evaluate pathogens causing acute infectious conjunctivitis in Burkina Faso. RESULTS: We found that pathogens causing conjunctivitis in Burkina Faso are diverse, with human adenoviruses responsible for a small fraction of the samples tested. CONCLUSIONS: These results are unexpected and suggest the importance of regional surveillance. Oxford University Press 2022-01-24 /pmc/articles/PMC9808514/ /pubmed/35076074 http://dx.doi.org/10.1093/inthealth/ihac001 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Short Communication
Bountogo, Mamadou
Sié, Ali
Coulibaly, Boubacar
Ruder, Kevin
Chen, Cindi
Zhong, Lina
Colby, Emily
Lebas, Elodie
Deiner, Michael
Hinterwirth, Armin
Lietman, Thomas M
Seitzman, Gerami D
Doan, Thuy
Deep sequencing analysis of acute conjunctivitis in Burkina Faso, Africa
title Deep sequencing analysis of acute conjunctivitis in Burkina Faso, Africa
title_full Deep sequencing analysis of acute conjunctivitis in Burkina Faso, Africa
title_fullStr Deep sequencing analysis of acute conjunctivitis in Burkina Faso, Africa
title_full_unstemmed Deep sequencing analysis of acute conjunctivitis in Burkina Faso, Africa
title_short Deep sequencing analysis of acute conjunctivitis in Burkina Faso, Africa
title_sort deep sequencing analysis of acute conjunctivitis in burkina faso, africa
topic Short Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808514/
https://www.ncbi.nlm.nih.gov/pubmed/35076074
http://dx.doi.org/10.1093/inthealth/ihac001
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