Estimation of intrafamilial DNA contamination in family trio genome sequencing using deviation from Mendelian inheritance

With the increasing number of sequencing projects involving families, quality control tools optimized for family genome sequencing are needed. However, accurately quantifying contamination in a DNA mixture is particularly difficult when genetically related family members are the sources. We develope...

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Detalles Bibliográficos
Autores principales: Yoon, Christopher J., Kim, Su Yeon, Nam, Chang Hyun, Lee, Junehawk, Park, Jung Woo, Mun, Jihyeob, Park, Seongyeol, Lee, Soyoung, Yi, Boram, Min, Kyoung Il, Wiley, Brian, Bolton, Kelly L., Lee, Jeong Ho, Kim, Eunjoon, Yoo, Hee Jeong, Jun, Jong Kwan, Choi, Ji Seon, Griffith, Malachi, Griffith, Obi L., Ju, Young Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2022
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808622/
https://www.ncbi.nlm.nih.gov/pubmed/36617634
http://dx.doi.org/10.1101/gr.276794.122

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