Cargando…
Retinal Vessel Phenotype in Patients with a History of Retinal Vein Occlusion
INTRODUCTION: The aim of the study was to estimate the phenotype of retinal vessels using central retinal artery equivalent (CRAE), central retinal vein equivalent (CRVE), tortuosity, and fractal analysis in the unaffected contralateral eye of patients with central or branch retinal vein occlusion (...
Autores principales: | , , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808644/ https://www.ncbi.nlm.nih.gov/pubmed/33910213 http://dx.doi.org/10.1159/000516235 |
_version_ | 1784862976526778368 |
---|---|
author | Semecas, Rachel Arnould, Louis Aptel, Florent Gavard, Olivier Mautuit, Thibaud Creuzot-Garcher, Catherine Bron, Alain MacGillivray, Tom Hogg, Stephen Trucco, Emmanuel Chiquet, Christophe |
author_facet | Semecas, Rachel Arnould, Louis Aptel, Florent Gavard, Olivier Mautuit, Thibaud Creuzot-Garcher, Catherine Bron, Alain MacGillivray, Tom Hogg, Stephen Trucco, Emmanuel Chiquet, Christophe |
author_sort | Semecas, Rachel |
collection | PubMed |
description | INTRODUCTION: The aim of the study was to estimate the phenotype of retinal vessels using central retinal artery equivalent (CRAE), central retinal vein equivalent (CRVE), tortuosity, and fractal analysis in the unaffected contralateral eye of patients with central or branch retinal vein occlusion (CRVO or BRVO). METHODS: Thirty-four patients suffering from CRVO, 15 suffering from BRVO, and 49 controlled matched subjects had a fundus image analyzed using the VAMPIRE software. The intraclass correlation coefficient and a Bland-Altman plot were done for the reproducibility study. RESULTS: There was a lack of evidence of difference between the control group and the CRVO group for CRAE (p = 0.06), CRVE (p = 0.3), and arterio-venule ratio (AVR, p = 0.6). Contralateral eyes of CRVO exhibited a significantly higher arterial and minimum arterial tortuosity values (p = 0.012), as compared with control eyes. Contralateral eyes of patients with a history of BRVO had a significantly higher CRAE (p = 0.02), AVR (p = 0.006), and minimal arterial tortuosity (p = 0.05). Fractal analysis showed that contralateral eyes of BRVO had higher values of fractal parameters (D0a, p = 0.005). CONCLUSION: This study suggests that CVRO or BRVO is not triggered by the same retinal vascular phenotypes in the contralateral eye. The morphology of retinal vasculature may be associated with the occurrence of RVO, independently of known risk factors. |
format | Online Article Text |
id | pubmed-9808644 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | S. Karger AG |
record_format | MEDLINE/PubMed |
spelling | pubmed-98086442023-01-04 Retinal Vessel Phenotype in Patients with a History of Retinal Vein Occlusion Semecas, Rachel Arnould, Louis Aptel, Florent Gavard, Olivier Mautuit, Thibaud Creuzot-Garcher, Catherine Bron, Alain MacGillivray, Tom Hogg, Stephen Trucco, Emmanuel Chiquet, Christophe Ophthalmic Res Research Article INTRODUCTION: The aim of the study was to estimate the phenotype of retinal vessels using central retinal artery equivalent (CRAE), central retinal vein equivalent (CRVE), tortuosity, and fractal analysis in the unaffected contralateral eye of patients with central or branch retinal vein occlusion (CRVO or BRVO). METHODS: Thirty-four patients suffering from CRVO, 15 suffering from BRVO, and 49 controlled matched subjects had a fundus image analyzed using the VAMPIRE software. The intraclass correlation coefficient and a Bland-Altman plot were done for the reproducibility study. RESULTS: There was a lack of evidence of difference between the control group and the CRVO group for CRAE (p = 0.06), CRVE (p = 0.3), and arterio-venule ratio (AVR, p = 0.6). Contralateral eyes of CRVO exhibited a significantly higher arterial and minimum arterial tortuosity values (p = 0.012), as compared with control eyes. Contralateral eyes of patients with a history of BRVO had a significantly higher CRAE (p = 0.02), AVR (p = 0.006), and minimal arterial tortuosity (p = 0.05). Fractal analysis showed that contralateral eyes of BRVO had higher values of fractal parameters (D0a, p = 0.005). CONCLUSION: This study suggests that CVRO or BRVO is not triggered by the same retinal vascular phenotypes in the contralateral eye. The morphology of retinal vasculature may be associated with the occurrence of RVO, independently of known risk factors. S. Karger AG 2021-04-28 /pmc/articles/PMC9808644/ /pubmed/33910213 http://dx.doi.org/10.1159/000516235 Text en Copyright © 2022 by The Author(s). Published by S. Karger AG, Basel https://creativecommons.org/licenses/by-nc/4.0/This article is licensed under the Creative Commons Attribution-NonCommercial 4.0 International License (CC BY-NC). Usage and distribution for commercial purposes requires written permission. |
spellingShingle | Research Article Semecas, Rachel Arnould, Louis Aptel, Florent Gavard, Olivier Mautuit, Thibaud Creuzot-Garcher, Catherine Bron, Alain MacGillivray, Tom Hogg, Stephen Trucco, Emmanuel Chiquet, Christophe Retinal Vessel Phenotype in Patients with a History of Retinal Vein Occlusion |
title | Retinal Vessel Phenotype in Patients with a History of Retinal Vein Occlusion |
title_full | Retinal Vessel Phenotype in Patients with a History of Retinal Vein Occlusion |
title_fullStr | Retinal Vessel Phenotype in Patients with a History of Retinal Vein Occlusion |
title_full_unstemmed | Retinal Vessel Phenotype in Patients with a History of Retinal Vein Occlusion |
title_short | Retinal Vessel Phenotype in Patients with a History of Retinal Vein Occlusion |
title_sort | retinal vessel phenotype in patients with a history of retinal vein occlusion |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808644/ https://www.ncbi.nlm.nih.gov/pubmed/33910213 http://dx.doi.org/10.1159/000516235 |
work_keys_str_mv | AT semecasrachel retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT arnouldlouis retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT aptelflorent retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT gavardolivier retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT mautuitthibaud retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT creuzotgarchercatherine retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT bronalain retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT macgillivraytom retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT hoggstephen retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT truccoemmanuel retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion AT chiquetchristophe retinalvesselphenotypeinpatientswithahistoryofretinalveinocclusion |