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Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar

Accurate determination of mortality attributable to SARS-CoV-2 vaccination is critical in allaying concerns about their safety. We reviewed every death in Qatar that occurred within 30 days of any SARS-CoV-2 vaccine administration between January 1, 2021 and June 12, 2022. Probability of association...

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Detalles Bibliográficos
Autores principales: Butt, Adeel A., Guerrero, Mylai D., Canlas, Elenor B., Al-Dwairi, Husni, Alimam, Abeir Bakhiet Mohammed Ali, Mohamad, Abdur Rehman, Ali, Mohammed Thamer, Asaad, Nidal Ahmad, Alkeldi, Ali Ahmed Sheikh Saleh, Mohammad, Mohammad Fawaz Saber, Thomas, Anil G., Al-Khal, Abdullatif, Al-Maslamani, Muna, Abou-Samra, Abdul-Badi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808756/
https://www.ncbi.nlm.nih.gov/pubmed/36596793
http://dx.doi.org/10.1038/s41467-022-35653-z
Descripción
Sumario:Accurate determination of mortality attributable to SARS-CoV-2 vaccination is critical in allaying concerns about their safety. We reviewed every death in Qatar that occurred within 30 days of any SARS-CoV-2 vaccine administration between January 1, 2021 and June 12, 2022. Probability of association with SARS-CoV-2 vaccination was determined by four independent trained reviewers using a modified WHO algorithm. Among 6,928,359 doses administered, 138 deaths occurred within 30 days of vaccination; eight had a high probability (1.15/1,000,000 doses), 15 had intermediate probability (2.38/1,000,000 doses), and 112 had low probability or no association with vaccination. The death rate among those with high probability of relationship to SARS-CoV-2 vaccination was 0.34/100,000 unique vaccine recipients, while death rate among those with either high or intermediate probability of relationship to SARS-CoV-2 vaccination was 0.98/100,000 unique vaccine recipients. In conclusion, deaths attributable to SARS-CoV-2 vaccination are extremely rare and lower than the overall crude mortality rate in Qatar.