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Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar
Accurate determination of mortality attributable to SARS-CoV-2 vaccination is critical in allaying concerns about their safety. We reviewed every death in Qatar that occurred within 30 days of any SARS-CoV-2 vaccine administration between January 1, 2021 and June 12, 2022. Probability of association...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808756/ https://www.ncbi.nlm.nih.gov/pubmed/36596793 http://dx.doi.org/10.1038/s41467-022-35653-z |
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author | Butt, Adeel A. Guerrero, Mylai D. Canlas, Elenor B. Al-Dwairi, Husni Alimam, Abeir Bakhiet Mohammed Ali Mohamad, Abdur Rehman Ali, Mohammed Thamer Asaad, Nidal Ahmad Alkeldi, Ali Ahmed Sheikh Saleh Mohammad, Mohammad Fawaz Saber Thomas, Anil G. Al-Khal, Abdullatif Al-Maslamani, Muna Abou-Samra, Abdul-Badi |
author_facet | Butt, Adeel A. Guerrero, Mylai D. Canlas, Elenor B. Al-Dwairi, Husni Alimam, Abeir Bakhiet Mohammed Ali Mohamad, Abdur Rehman Ali, Mohammed Thamer Asaad, Nidal Ahmad Alkeldi, Ali Ahmed Sheikh Saleh Mohammad, Mohammad Fawaz Saber Thomas, Anil G. Al-Khal, Abdullatif Al-Maslamani, Muna Abou-Samra, Abdul-Badi |
author_sort | Butt, Adeel A. |
collection | PubMed |
description | Accurate determination of mortality attributable to SARS-CoV-2 vaccination is critical in allaying concerns about their safety. We reviewed every death in Qatar that occurred within 30 days of any SARS-CoV-2 vaccine administration between January 1, 2021 and June 12, 2022. Probability of association with SARS-CoV-2 vaccination was determined by four independent trained reviewers using a modified WHO algorithm. Among 6,928,359 doses administered, 138 deaths occurred within 30 days of vaccination; eight had a high probability (1.15/1,000,000 doses), 15 had intermediate probability (2.38/1,000,000 doses), and 112 had low probability or no association with vaccination. The death rate among those with high probability of relationship to SARS-CoV-2 vaccination was 0.34/100,000 unique vaccine recipients, while death rate among those with either high or intermediate probability of relationship to SARS-CoV-2 vaccination was 0.98/100,000 unique vaccine recipients. In conclusion, deaths attributable to SARS-CoV-2 vaccination are extremely rare and lower than the overall crude mortality rate in Qatar. |
format | Online Article Text |
id | pubmed-9808756 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-98087562023-01-04 Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar Butt, Adeel A. Guerrero, Mylai D. Canlas, Elenor B. Al-Dwairi, Husni Alimam, Abeir Bakhiet Mohammed Ali Mohamad, Abdur Rehman Ali, Mohammed Thamer Asaad, Nidal Ahmad Alkeldi, Ali Ahmed Sheikh Saleh Mohammad, Mohammad Fawaz Saber Thomas, Anil G. Al-Khal, Abdullatif Al-Maslamani, Muna Abou-Samra, Abdul-Badi Nat Commun Article Accurate determination of mortality attributable to SARS-CoV-2 vaccination is critical in allaying concerns about their safety. We reviewed every death in Qatar that occurred within 30 days of any SARS-CoV-2 vaccine administration between January 1, 2021 and June 12, 2022. Probability of association with SARS-CoV-2 vaccination was determined by four independent trained reviewers using a modified WHO algorithm. Among 6,928,359 doses administered, 138 deaths occurred within 30 days of vaccination; eight had a high probability (1.15/1,000,000 doses), 15 had intermediate probability (2.38/1,000,000 doses), and 112 had low probability or no association with vaccination. The death rate among those with high probability of relationship to SARS-CoV-2 vaccination was 0.34/100,000 unique vaccine recipients, while death rate among those with either high or intermediate probability of relationship to SARS-CoV-2 vaccination was 0.98/100,000 unique vaccine recipients. In conclusion, deaths attributable to SARS-CoV-2 vaccination are extremely rare and lower than the overall crude mortality rate in Qatar. Nature Publishing Group UK 2023-01-03 /pmc/articles/PMC9808756/ /pubmed/36596793 http://dx.doi.org/10.1038/s41467-022-35653-z Text en © The Author(s) 2023 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Butt, Adeel A. Guerrero, Mylai D. Canlas, Elenor B. Al-Dwairi, Husni Alimam, Abeir Bakhiet Mohammed Ali Mohamad, Abdur Rehman Ali, Mohammed Thamer Asaad, Nidal Ahmad Alkeldi, Ali Ahmed Sheikh Saleh Mohammad, Mohammad Fawaz Saber Thomas, Anil G. Al-Khal, Abdullatif Al-Maslamani, Muna Abou-Samra, Abdul-Badi Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar |
title | Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar |
title_full | Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar |
title_fullStr | Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar |
title_full_unstemmed | Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar |
title_short | Evaluation of mortality attributable to SARS-CoV-2 vaccine administration using national level data from Qatar |
title_sort | evaluation of mortality attributable to sars-cov-2 vaccine administration using national level data from qatar |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808756/ https://www.ncbi.nlm.nih.gov/pubmed/36596793 http://dx.doi.org/10.1038/s41467-022-35653-z |
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