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Immune Responses and Immunosuppressive Strategies for Adeno-Associated Virus-Based Gene Therapy for Treatment of Central Nervous System Disorders: Current Knowledge and Approaches

Adeno-associated viruses (AAVs) are being increasingly used as gene therapy vectors in clinical studies especially targeting central nervous system (CNS) disorders. Correspondingly, host immune responses to the AAV capsid or the transgene-encoded protein have been observed in various clinical and pr...

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Detalles Bibliográficos
Autores principales:	Prasad, Suyash, Dimmock, David P., Greenberg, Benjamin, Walia, Jagdeep S., Sadhu, Chanchal, Tavakkoli, Fatemeh, Lipshutz, Gerald S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Mary Ann Liebert, Inc., publishers 2022
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808800/ https://www.ncbi.nlm.nih.gov/pubmed/35994385 http://dx.doi.org/10.1089/hum.2022.138

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