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Afatinib plus osimertinib in the treatment of osimertinib-resistant non-small cell lung carcinoma: a phase I clinical trial

BACKGROUND: Conquering acquired resistance to osimertinib remains a major challenge in treating patients with epidermal growth factor receptor (EGFR) mutation-positive non-small-cell lung cancer (NSCLC). Thus, we aimed to determine the safety and efficacy of combination treatment with osimertinib an...

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Detalles Bibliográficos
Autores principales:	Miura, Satoru, Koh, Yasuhiro, Azuma, Koichi, Yoshioka, Hiroshige, Koyama, Kenichi, Teraoka, Shunsuke, Ishii, Hidenobu, Kibata, Kayoko, Ozawa, Yuichi, Tokito, Takaaki, Oyanagi, Jun, Shimokawa, Toshio, Kurata, Takayasu, Yamamoto, Nobuyuki, Tanaka, Hiroshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808978/ https://www.ncbi.nlm.nih.gov/pubmed/36597021 http://dx.doi.org/10.1186/s12885-022-10467-w

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