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(Pro)renin receptor promotes colorectal cancer progression through inhibiting the NEDD4L-mediated Wnt3 ubiquitination and modulating gut microbiota

BACKGROUND: We previously found that (pro)renin receptor ((P)RR) augments Wnt3 protein without affecting Wnt3 gene transcription in colorectal cancer (CRC) cells, thus contributes to CRC initiation. The present study aims to investigate whether (P)RR further promotes CRC progression following oncoge...

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Detalles Bibliográficos
Autores principales:	Wang, Juan, Ding, Yuwei, Li, Dan, Zhu, Ning, Nishiyama, Akira, Yuan, Ying
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809055/ https://www.ncbi.nlm.nih.gov/pubmed/36597142 http://dx.doi.org/10.1186/s12964-022-01015-x

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