The E3 ubiquitin ligase TRIM31 attenuates NLRP3 inflammasome activation in Helicobacter pylori-associated gastritis by regulating ROS and autophagy

BACKGROUND: The NLRP3 inflammasome activation is the molecular basis of Helicobacter pylori (Hp)-associated gastritis. Tripartite motif (TRIM) 31 is involved in diverse pathological events. However, whether TRIM31 plays a role in the activation of NLRP3 inflammasome in Hp infection is not clarified....

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Detalles Bibliográficos
Autores principales: Yu, Qiao, Shi, Huiying, Ding, Zhen, Wang, Zhe, Yao, Hailing, Lin, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809066/
https://www.ncbi.nlm.nih.gov/pubmed/36597090
http://dx.doi.org/10.1186/s12964-022-00954-9

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