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Relapsing COVID-19 infection as a manifestation of Good syndrome: a case report and literature review

Good syndrome (GS) is a rare acquired immunodeficiency disease characterized by the presence of thymoma with combined B and T cell immunodeficiency in adults. Recurrent bacterial infections, particularly sinopulmonary infections caused by encapsulated bacteria, remain the most common infective prese...

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Autores principales: Wee, Liang En, Tan, Jing Yuan, Oon, Lynette Lin Ean, Pena, Angela Maria Takano, Quek, Jeffrey Kim Siang, Venkatachalam, Indumathi, Ko, Karrie Kwan-Ki, Wijaya, Limin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809144/
https://www.ncbi.nlm.nih.gov/pubmed/36608786
http://dx.doi.org/10.1016/j.ijid.2022.12.040
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author Wee, Liang En
Tan, Jing Yuan
Oon, Lynette Lin Ean
Pena, Angela Maria Takano
Quek, Jeffrey Kim Siang
Venkatachalam, Indumathi
Ko, Karrie Kwan-Ki
Wijaya, Limin
author_facet Wee, Liang En
Tan, Jing Yuan
Oon, Lynette Lin Ean
Pena, Angela Maria Takano
Quek, Jeffrey Kim Siang
Venkatachalam, Indumathi
Ko, Karrie Kwan-Ki
Wijaya, Limin
author_sort Wee, Liang En
collection PubMed
description Good syndrome (GS) is a rare acquired immunodeficiency disease characterized by the presence of thymoma with combined B and T cell immunodeficiency in adults. Recurrent bacterial infections, particularly sinopulmonary infections caused by encapsulated bacteria, remain the most common infective presentation of GS; however, relapsing viral infections have also been reported, likely due to impaired T cell-mediated immunity. Relapsing COVID-19 infection, however, has not been previously reported as a manifestation of GS. We present two cases of relapsing COVID-19 infection in patients with GS; in one case, relapsing COVID-19 was the first manifestation of newly diagnosed GS.
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spelling pubmed-98091442023-01-04 Relapsing COVID-19 infection as a manifestation of Good syndrome: a case report and literature review Wee, Liang En Tan, Jing Yuan Oon, Lynette Lin Ean Pena, Angela Maria Takano Quek, Jeffrey Kim Siang Venkatachalam, Indumathi Ko, Karrie Kwan-Ki Wijaya, Limin Int J Infect Dis Article Good syndrome (GS) is a rare acquired immunodeficiency disease characterized by the presence of thymoma with combined B and T cell immunodeficiency in adults. Recurrent bacterial infections, particularly sinopulmonary infections caused by encapsulated bacteria, remain the most common infective presentation of GS; however, relapsing viral infections have also been reported, likely due to impaired T cell-mediated immunity. Relapsing COVID-19 infection, however, has not been previously reported as a manifestation of GS. We present two cases of relapsing COVID-19 infection in patients with GS; in one case, relapsing COVID-19 was the first manifestation of newly diagnosed GS. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2023-04 2023-01-03 /pmc/articles/PMC9809144/ /pubmed/36608786 http://dx.doi.org/10.1016/j.ijid.2022.12.040 Text en © 2022 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Wee, Liang En
Tan, Jing Yuan
Oon, Lynette Lin Ean
Pena, Angela Maria Takano
Quek, Jeffrey Kim Siang
Venkatachalam, Indumathi
Ko, Karrie Kwan-Ki
Wijaya, Limin
Relapsing COVID-19 infection as a manifestation of Good syndrome: a case report and literature review
title Relapsing COVID-19 infection as a manifestation of Good syndrome: a case report and literature review
title_full Relapsing COVID-19 infection as a manifestation of Good syndrome: a case report and literature review
title_fullStr Relapsing COVID-19 infection as a manifestation of Good syndrome: a case report and literature review
title_full_unstemmed Relapsing COVID-19 infection as a manifestation of Good syndrome: a case report and literature review
title_short Relapsing COVID-19 infection as a manifestation of Good syndrome: a case report and literature review
title_sort relapsing covid-19 infection as a manifestation of good syndrome: a case report and literature review
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809144/
https://www.ncbi.nlm.nih.gov/pubmed/36608786
http://dx.doi.org/10.1016/j.ijid.2022.12.040
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