Cargando…

Restoring mortality data in the FOURIER cardiovascular outcomes trial of evolocumab in patients with cardiovascular disease: a reanalysis based on regulatory data

OBJECTIVE: The FOURIER trial showed a benefit of the PCSK9 inhibitor evolocumab over placebo with respect to cardiovascular outcomes in patients with cardiovascular disease. However, we observed some inconsistencies between the information in the Clinical Study Report (CSR) and that in the 2017 prim...

Descripción completa

Detalles Bibliográficos
Autores principales:	Erviti, Juan, Wright, James, Bassett, Ken, Ben-Eltriki, Mohamed, Jauca, Ciprian, Saiz, Luis Carlos, Leache, Leire, Gutiérrez-Valencia, Marta, Perry, Thomas L
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Cardiovascular Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809302/ https://www.ncbi.nlm.nih.gov/pubmed/36585131 http://dx.doi.org/10.1136/bmjopen-2021-060172

Ejemplares similares

Restoring Study PRGF: a randomized clinical trial on plasma rich in growth factors for knee osteoarthritis
por: Saiz, Luis Carlos, et al.
Publicado: (2023)

Evolocumab to reduce cardiovascular events: results of the (FOURIER) multinational trial
por: Shah, Syed Raza, et al.
Publicado: (2017)

Medical journals and editorial quality control
por: Erviti, Juan, et al.
Publicado: (2019)

Incidence of Attention Deficit Hyperactivity Disorder (ADHD) Diagnoses in Navarre (Spain) from 2003 to 2019
por: Leache, Leire, et al.
Publicado: (2021)

Efficacy and safety of chimeric antigen receptor T-cell (CAR-T) therapy in hematologic malignancies: a living systematic review on comparative studies
por: Saiz, Luis Carlos, et al.
Publicado: (2023)

Effects of Evolocumab on Cardiovascular Events
por: Mikhail, Nasser
Publicado: (2017)

Effect of alirocumab and evolocumab on all-cause mortality and major cardiovascular events: A meta-analysis focusing on the number needed to treat
por: Wang, Hong-Fei, et al.
Publicado: (2022)

Evolocumab’s Long-Term Mortality Risk Unclear Due to Shortened Follow-Up of FOURIER
por: van Bruggen, Folkert H., et al.
Publicado: (2021)

Cost-Effectiveness Analysis of Evolocumab in Adult Patients with Atherosclerotic Cardiovascular Disease in Canada
por: Grégoire, Jean, et al.
Publicado: (2022)

FRI097 A Case Of Evolocumab-induced Transaminitis Revealing A Gastrointestinal Melanoma
por: Nava Suarez, Corina, et al.
Publicado: (2023)

Why we need a single independent international hypertension clinical practice guideline
por: Ben-Eltriki, Mohamed, et al.
Publicado: (2021)

Cost‐Effectiveness of LDL‐C Lowering With Evolocumab in Patients With High Cardiovascular Risk in the United States
por: Gandra, Shravanthi R., et al.
Publicado: (2016)

Smallpox and Season: Reanalysis of Historical Data
por: Nishiura, Hiroshi, et al.
Publicado: (2009)

Lipid‐lowering treatment patterns in patients with new cardiovascular events – estimates from population‐based register data in Sweden
por: Hallberg, S., et al.
Publicado: (2016)

Guidelines for Cardiovascular Magnetic Resonance Imaging from the Korean Society of Cardiovascular Imaging—Part 2: Interpretation of Cine, Flow, and Angiography Data
por: Lee, Jae Wook, et al.
Publicado: (2019)

Use of Multi-Modal Data and Machine Learning to Improve Cardiovascular Disease Care
por: Amal, Saeed, et al.
Publicado: (2022)

Artificial intelligence applications in cardio-oncology: Leveraging high dimensional cardiovascular data
por: Chen, Haidee, et al.
Publicado: (2022)

Data Assimilation by Stochastic Ensemble Kalman Filtering to Enhance Turbulent Cardiovascular Flow Data From Under-Resolved Observations
por: De Marinis, Dario, et al.
Publicado: (2021)

Chronic Stress-Related Neural Activity Associates With Subclinical Cardiovascular Disease in a Community-Based Cohort: Data From the Washington, D.C. Cardiovascular Health and Needs Assessment
por: Powell-Wiley, Tiffany M., et al.
Publicado: (2021)

Assessment of cardiovascular risk in Tunisia: applying the Framingham risk score to national survey data
por: Saidi, O, et al.
Publicado: (2016)

Association of height loss and cardiovascular disease: Data from a large Korean cohort
por: Moon, Jeonggeun, et al.
Publicado: (2022)

Machine learning with sparse nutrition data to improve cardiovascular mortality risk prediction in the USA using nationally randomly sampled data
por: Rigdon, Joseph, et al.
Publicado: (2019)

Response: A Reanalysis of Sperm Density Data
por: Swan, Shanna H., et al.
Publicado: (1998)

Acute Kidney Injury associated with "Triple whammy" combination: a protocol for a systematic review.
por: Calvo Barbado, Dulce Maria, et al.
Publicado: (2022)

Editorial: Systems biology and data-driven machine learning-based models in personalized cardiovascular medicine
por: Hueso, Miguel, et al.
Publicado: (2023)

Evolocumab enables rapid LDL-C reduction and inflammatory modulation during in-hospital stage of acute coronary syndrome: A pilot study on Chinese patients
por: Ou, Ziwei, et al.
Publicado: (2022)

Prevalence and significance of early repolarisation in a black African population: data of 246 individuals with cardiovascular morbidity
por: Bonny, Aime, et al.
Publicado: (2013)

The addition of genetic testing and cardiovascular magnetic resonance to routine clinical data for stratification of etiology in dilated cardiomyopathy
por: Amin, Ravi J., et al.
Publicado: (2022)

Reanalysis of quarantine for coronavirus disease 2019 with emerging data
por: Cimolai, Nevio
Publicado: (2021)

Role of Cardiovascular Magnetic Resonance to Assess Cardiovascular Inflammation
por: Filomena, Domenico, et al.
Publicado: (2022)

The Effect of the PCSK9 Inhibitor Evolocumab on Aldosterone Secretion among High Cardiovascular Risk Patients: A Pilot Study
por: Izkhakov, Elena, et al.
Publicado: (2021)

Lipid lowering effects and safety of evolocumab in Chinese patients at very high cardiovascular risk: a single-center study
por: Chai, Meng, et al.
Publicado: (2023)

Underutilisation of cardiovascular medications among at-risk individuals
por: Lewis, S J, et al.
Publicado: (2010)

Editorial: Insights in cardiovascular therapeutics: 2021 – cell death, cardiovascular injuries, and novel targets of cardiovascular therapeutics
por: Xu, Keman, et al.
Publicado: (2022)

Painful and recurring injection site reaction to alirocumab and evolocumab in a young woman with familial hypercholesterolemia and effective therapeutic alternative based on inclisiran: a case report
por: Allevi, Massimiliano, et al.
Publicado: (2023)

Cardiovascular News
Publicado: (2017)

Cardiovascular News
por: Velupandian, Uma
Publicado: (2020)

Cardiovascular News
por: Velupandian, Uma
Publicado: (2020)

Cardiovascular News
por: Albizreh, Bassim
Publicado: (2021)

Ideal Cardiovascular Health in Young Adults With Established Cardiovascular Diseases
por: Leopold, Jane A., et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_heokkmagtprcfc616ndrj9ra3u