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Yap signalling regulates ductular reactions in mice with CRISPR/Cas9-induced glycogen storage disease type Ia
Glycogen storage disease type Ia (GSD-Ia) is caused by a deficiency in the glucose-6-phosphatase (G6Pase, G6pc) enzyme, which catalyses the final step of gluconeogenesis and glycogenolysis. Accumulation of G6pc can lead to an increase in glycogen and development of fatty liver. Ductular reactions re...
Autores principales: | Xie, Yixia, Hu, Baowei, Gao, Yue, Tang, Yaxin, Chen, Guohe, Shen, Jiayuan, Jiang, Zhikai, Jiang, He, Han, Jiwei, Yan, Junyan, Jin, Lifang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809376/ https://www.ncbi.nlm.nih.gov/pubmed/36605584 http://dx.doi.org/10.1080/19768354.2022.2139755 |
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