Cargando…

A focused natural compound screen reveals senolytic and senostatic effects of Isatis tinctoria

Natural products and their derivatives historically represent alternatives to conventional synthetic molecules for pharmacotherapy, ranging from cancer chemotherapeutics to cosmetic ingredients that exert anti-aging activities. Cellular senescence is considered a main driver of skin aging, yet natur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kim, Eun-Jung, Woo, Jieun, Shin, Seoungwoo, Choi, HaeBeen, Kim, Youngseok, Kim, Junoh, Kang, Chanhee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2022
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809397/ https://www.ncbi.nlm.nih.gov/pubmed/36605596 http://dx.doi.org/10.1080/19768354.2022.2143895

Ejemplares similares

Isatis tinctoria L. Leaf Extract Inhibits Replicative Senescence in Dermal Fibroblasts by Regulating mTOR-NF-κB-SASP Signaling
por: Woo, Jieun, et al.
Publicado: (2022)

Senolytics and senostatics as adjuvant tumour therapy
por: Short, Susan, et al.
Publicado: (2019)

Senolytics and Senostatics: A Two-Pronged Approach to Target Cellular Senescence for Delaying Aging and Age-Related Diseases
por: Kang, Chanhee
Publicado: (2019)

An Appraisal on the Value of Using Nutraceutical Based Senolytics and Senostatics in Aging
por: Kaur, Amanpreet, et al.
Publicado: (2020)

Short senolytic or senostatic interventions rescue progression of radiation-induced frailty and premature ageing in mice
por: Fielder, Edward, et al.
Publicado: (2022)

Classification of Isatis indigotica Fortune and Isatis tinctoria Linnaeus via comparative analysis of chloroplast genomes
por: Su, Yong, et al.
Publicado: (2023)

Structure Analysis of Effective Chemical Compounds against Dengue Viruses Isolated from Isatis tinctoria
por: Gao, Bo, et al.
Publicado: (2018)

Alkaloids with Nitric Oxide Inhibitory Activities from the Roots of Isatis tinctoria
por: Zhang, Dongdong, et al.
Publicado: (2019)

Solvent polarity mediates phytochemical yield and antioxidant capacity of Isatis tinctoria
por: Wakeel, Abdul, et al.
Publicado: (2019)

Microscopic Mass Spectrometry Imaging Reveals the Distribution of Phytochemicals in the Dried Root of Isatis tinctoria
por: Nie, Li-Xing, et al.
Publicado: (2021)

AMPK-mediated senolytic and senostatic activity of quercetin surface functionalized Fe(3)O(4) nanoparticles during oxidant-induced senescence in human fibroblasts
por: Lewinska, Anna, et al.
Publicado: (2019)

Inhibitory effect of Isatis tinctoria L. water extract on DNCB-induced atopic dermatitis in BALB/c mice and HaCaT cells
por: Min, Ga-Yul, et al.
Publicado: (2022)

In Silico Prediction and Bioactivity Evaluation of Chemical Ingredients Against Influenza A Virus From Isatis tinctoria L
por: Cai, Chuipu, et al.
Publicado: (2021)

Isatis tinctoria L. (Woad): A Review of Its Botany, Ethnobotanical Uses, Phytochemistry, Biological Activities, and Biotechnological Studies
por: Speranza, Jasmine, et al.
Publicado: (2020)

Improvement in the Biosynthesis of Antioxidant-Active Metabolites in In Vitro Cultures of Isatis tinctoria (Brassicaceae) by Biotechnological Methods/Elicitation and Precursor Feeding
por: Miceli, Natalizia, et al.
Publicado: (2023)

Chitosan elicitation of Isatis tinctoria L. hairy root cultures for enhancing flavonoid productivity and gene expression and related antioxidant activity
por: Jiao, Jiao, et al.
Publicado: (2018)

Ultraviolet radiation for flavonoid augmentation in Isatis tinctoria L. hairy root cultures mediated by oxidative stress and biosynthetic gene expression
por: Jiao, Jiao, et al.
Publicado: (2018)

In Vitro Anthelmintic Activity of Isatis tinctoria Extracts against Ewes’ Gastrointestinal Nematodes (GINs), a Possible Application for Animal Welfare
por: Ragusa, Monica, et al.
Publicado: (2022)

Establishment of Hairy Root Cultures by Agrobacterium Rhizogenes Mediated Transformation of Isatis Tinctoria L. for the Efficient Production of Flavonoids and Evaluation of Antioxidant Activities
por: Gai, Qing-Yan, et al.
Publicado: (2015)

Remarkable enhancement of flavonoid production in a co-cultivation system of Isatis tinctoria L. hairy root cultures and immobilized Aspergillus niger
por: Jiao, Jiao, et al.
Publicado: (2018)

Hydroalcoholic Leaf Extract of Isatis tinctoria L. via Antioxidative and Anti-Inflammatory Effects Reduces Stress-Induced Behavioral and Cellular Disorders in Mice
por: Nicosia, Noemi, et al.
Publicado: (2022)

Chemoinformatic Screening for the Selection of Potential Senolytic Compounds from Natural Products
por: Barrera-Vázquez, Oscar Salvador, et al.
Publicado: (2021)

Isatis tinctoria L.-derived Petroleum Ether Extract Mediates Anti-inflammatory Effects via Inhibition of Interleukin-6, Interleukin-33 and Mast Cell Degranulation
por: LOTTS, Tobias, et al.
Publicado: (2020)

Identification and characterization of Cardiac Glycosides as senolytic compounds
por: Triana-Martínez, Francisco, et al.
Publicado: (2019)

Multi-analytical study of the medieval wall paintings from the rupestrian church Grotta del Crocifisso at Lentini (eastern Sicily): new evidence of the use of woad (Isatis tinctoria)
por: Montana, Giuseppe, et al.
Publicado: (2022)

Baptisia Tinctoria
por: Sherbino, G. W.
Publicado: (1889)

Baptistæ Tinctoria
Publicado: (1847)

Identification of gingerenone A as a novel senolytic compound
por: Moaddel, Ruin, et al.
Publicado: (2022)

Senolytic Therapy for Cerebral Ischemia-Reperfusion Injury
por: Lim, Songhyun, et al.
Publicado: (2021)

Paradoxes of senolytics
por: Blagosklonny, Mikhail V.
Publicado: (2018)

Biosynthesis of the active compounds of Isatis indigotica based on transcriptome sequencing and metabolites profiling
por: Chen, Junfeng, et al.
Publicado: (2013)

Senescence and Senolytics: State of the Art on Cellular Senescence, Senolytics, and Healthspan
por: Campisi, Judith
Publicado: (2020)

Mitochondrial Aging and Senolytic Natural Products with Protective Potential
por: Deledda, Andrea, et al.
Publicado: (2022)

Author Correction: Identification and characterization of Cardiac Glycosides as senolytic compounds
por: Triana-Martínez, Francisco, et al.
Publicado: (2020)

Nintedanib induces senolytic effect via STAT3 inhibition
por: Cho, Hyun-Ji, et al.
Publicado: (2022)

Identification of SYK inhibitor, R406 as a novel senolytic agent
por: Cho, Hyun-Ji, et al.
Publicado: (2020)

Alkaloid Enantiomers from the Roots of Isatis indigotica
por: Zhang, Dongdong, et al.
Publicado: (2019)

Metformin as a senostatic drug enhances the anticancer efficacy of CDK4/6 inhibitor in head and neck squamous cell carcinoma
por: Hu, Qinchao, et al.
Publicado: (2020)

A chromosome-scale genome assembly of Isatis indigotica, an important medicinal plant used in traditional Chinese medicine: An Isatis genome
por: Kang, Minghui, et al.
Publicado: (2020)

Antimicrobial and lipase inhibition of essential oil and solvent extracts of Cota tinctoria var. tinctoria and characterization of the essential oil
por: ERİK, İshak, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_mj3snup8lp42ku4silnsip9o74