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Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study

INTRODUCTION: Microalbuminuria presents significant health risks for the progression of endstage renal-failure (ESRF) among type 2 diabetes mellitus (T2DM) patients. This study aims to determine the proportion and associated factors of microalbuminuria among T2DM patients in Kuala Selangor district,...

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Autores principales: Shahrir, Nurul Farehah, Aziz, Noor Rafizah Aminah, Ahmad, Fatimah Lailiza, Muzaid, Nor Anizah, Samat, Farhani, Syed Ghazaili, Sharifah Nurul Aida, Dolbasir, Nuraini, Baharum, Nurul Nadia, T. Ramanathan, Sharmilee, Abd Rahman, Siti Zaharah, Bat, Ap. Sa’aidah, Sarif, Maznah, Ismaal, Noor Afiza
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academy of Family Physician of Malaysia 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809433/
https://www.ncbi.nlm.nih.gov/pubmed/36606172
http://dx.doi.org/10.51866/oa.122
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author Shahrir, Nurul Farehah
Aziz, Noor Rafizah Aminah
Ahmad, Fatimah Lailiza
Muzaid, Nor Anizah
Samat, Farhani
Syed Ghazaili, Sharifah Nurul Aida
Dolbasir, Nuraini
Baharum, Nurul Nadia
T. Ramanathan, Sharmilee
Abd Rahman, Siti Zaharah
Bat, Ap. Sa’aidah
Sarif, Maznah
Ismaal, Noor Afiza
author_facet Shahrir, Nurul Farehah
Aziz, Noor Rafizah Aminah
Ahmad, Fatimah Lailiza
Muzaid, Nor Anizah
Samat, Farhani
Syed Ghazaili, Sharifah Nurul Aida
Dolbasir, Nuraini
Baharum, Nurul Nadia
T. Ramanathan, Sharmilee
Abd Rahman, Siti Zaharah
Bat, Ap. Sa’aidah
Sarif, Maznah
Ismaal, Noor Afiza
author_sort Shahrir, Nurul Farehah
collection PubMed
description INTRODUCTION: Microalbuminuria presents significant health risks for the progression of endstage renal-failure (ESRF) among type 2 diabetes mellitus (T2DM) patients. This study aims to determine the proportion and associated factors of microalbuminuria among T2DM patients in Kuala Selangor district, Malaysia. METHOD: A retrospective cross-sectional study was conducted from December 2020 to February 2021 using secondary data from the National Diabetic Registry (NDR), Malaysia, and reviewed patients’ diabetic records for the year 2020. All T2DM patients aged >18 years who were registered with the NDR in 2020 and fulfilled the inclusion and exclusion criteria were included in the study. Descriptive statistics and multiple logistic regression analysis were performed. Data were analysed using SPSS version 26.0. A total of 343 samples were included in this study for the determination of the proportion of microalbuminuria and its associated factors. RESULTS: Of 343 respondents, 34.4% had microalbuminuria. HbAlc >7.0% (AdjOR 2.19, 95% CI: 1.35, 3.55, p=0.001), HDL <1.04 mmol/L (AdjOR 2.44, 95% CI: 1.323, 4.52, p=0.004), dyslipidaemia (AdjOR 1.90, 95% CI: 1.03, 3.48, p=0.039), and peripheral neuropathy (AdjOR 3.01, 95% CI: 1.02, 8.93, p=0.047) were significantly associated with microalbuminuria. Conclusion: Microalbuminuria is a modifiable risk factor in preventing the progression of ESRF among T2DM patients. Therefore, identification of factors associated with microalbuminuria among this high-risk group is important to facilitate early screening and prompt treatment to prevent progression of diabetic kidney disease to ESRF.
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spelling pubmed-98094332023-01-04 Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study Shahrir, Nurul Farehah Aziz, Noor Rafizah Aminah Ahmad, Fatimah Lailiza Muzaid, Nor Anizah Samat, Farhani Syed Ghazaili, Sharifah Nurul Aida Dolbasir, Nuraini Baharum, Nurul Nadia T. Ramanathan, Sharmilee Abd Rahman, Siti Zaharah Bat, Ap. Sa’aidah Sarif, Maznah Ismaal, Noor Afiza Malays Fam Physician Original Article INTRODUCTION: Microalbuminuria presents significant health risks for the progression of endstage renal-failure (ESRF) among type 2 diabetes mellitus (T2DM) patients. This study aims to determine the proportion and associated factors of microalbuminuria among T2DM patients in Kuala Selangor district, Malaysia. METHOD: A retrospective cross-sectional study was conducted from December 2020 to February 2021 using secondary data from the National Diabetic Registry (NDR), Malaysia, and reviewed patients’ diabetic records for the year 2020. All T2DM patients aged >18 years who were registered with the NDR in 2020 and fulfilled the inclusion and exclusion criteria were included in the study. Descriptive statistics and multiple logistic regression analysis were performed. Data were analysed using SPSS version 26.0. A total of 343 samples were included in this study for the determination of the proportion of microalbuminuria and its associated factors. RESULTS: Of 343 respondents, 34.4% had microalbuminuria. HbAlc >7.0% (AdjOR 2.19, 95% CI: 1.35, 3.55, p=0.001), HDL <1.04 mmol/L (AdjOR 2.44, 95% CI: 1.323, 4.52, p=0.004), dyslipidaemia (AdjOR 1.90, 95% CI: 1.03, 3.48, p=0.039), and peripheral neuropathy (AdjOR 3.01, 95% CI: 1.02, 8.93, p=0.047) were significantly associated with microalbuminuria. Conclusion: Microalbuminuria is a modifiable risk factor in preventing the progression of ESRF among T2DM patients. Therefore, identification of factors associated with microalbuminuria among this high-risk group is important to facilitate early screening and prompt treatment to prevent progression of diabetic kidney disease to ESRF. Academy of Family Physician of Malaysia 2022-08-25 /pmc/articles/PMC9809433/ /pubmed/36606172 http://dx.doi.org/10.51866/oa.122 Text en © Academy of Family Physicians of Malaysia https://creativecommons.org/licenses/by/4.0/Open Access: This is an Open Access article licensed under the Creative Commons Attribution (CC BY 4.0) license, which permits others to distribute, remix, adapt and build upon this work, for commercial use, provided the original author(s) and source are properly cited. See: http://creativecommons.org/licenses/by/4.0/
spellingShingle Original Article
Shahrir, Nurul Farehah
Aziz, Noor Rafizah Aminah
Ahmad, Fatimah Lailiza
Muzaid, Nor Anizah
Samat, Farhani
Syed Ghazaili, Sharifah Nurul Aida
Dolbasir, Nuraini
Baharum, Nurul Nadia
T. Ramanathan, Sharmilee
Abd Rahman, Siti Zaharah
Bat, Ap. Sa’aidah
Sarif, Maznah
Ismaal, Noor Afiza
Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study
title Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study
title_full Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study
title_fullStr Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study
title_full_unstemmed Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study
title_short Determinants of microalbuminuria among type 2 diabetes mellitus patients in Kuala Selangor district: A cross-sectional study
title_sort determinants of microalbuminuria among type 2 diabetes mellitus patients in kuala selangor district: a cross-sectional study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809433/
https://www.ncbi.nlm.nih.gov/pubmed/36606172
http://dx.doi.org/10.51866/oa.122
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