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Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome

There is no well-established procedure for the management of small penis syndrome (SPS), especially when psychological interventions fail. This study aimed at systematically evaluating the physical and psychological benefits of penile augmentation (PA) using injectable hyaluronic acid (HA) gel. Thir...

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Autores principales: Zhang, Chun-Long, Quan, Yuan, Li, He, Li, Qing, Bai, Wen-Jun, Xu, Tao, Zhang, Xiao-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809476/
https://www.ncbi.nlm.nih.gov/pubmed/35417989
http://dx.doi.org/10.4103/aja20223
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author Zhang, Chun-Long
Quan, Yuan
Li, He
Li, Qing
Bai, Wen-Jun
Xu, Tao
Zhang, Xiao-Wei
author_facet Zhang, Chun-Long
Quan, Yuan
Li, He
Li, Qing
Bai, Wen-Jun
Xu, Tao
Zhang, Xiao-Wei
author_sort Zhang, Chun-Long
collection PubMed
description There is no well-established procedure for the management of small penis syndrome (SPS), especially when psychological interventions fail. This study aimed at systematically evaluating the physical and psychological benefits of penile augmentation (PA) using injectable hyaluronic acid (HA) gel. Thirty-eight patients receiving PA with HA gel from January 2017 to March 2020 were included and followed up for 1 year. Penile size, erectile function, and psychological burden measured by the Index of Male Genital Image (IMGI), Index of International Erectile Function (IIEF), and Beliefs about Penis Size (BPAS), respectively, were assessed at the beginning and at 1, 3, 6, and 12 months postinjection. The volume of HA gel injected was 21.5 ± 3.7 ml. Compared to baseline data, flaccid penile girth and length significantly increased by 3.41 ± 0.95 cm (P < 0.01) and 2.55 ± 0.55 cm (P < 0.01) at the 1(st) month postinjection, respectively. At the endpoint, despite attenuations, statistically significant improvements in flaccid penis size were still obtained, namely 2.44 ± 1.14 cm in girth (P < 0.01) and 1.65 ± 0.59 cm in length (P < 0.01). Similarly, erectile penile girth statistically increased by 1.32 ± 1.02 cm (P < 0.01) at the 1(st) month but were only 0.80 ± 0.54 cm bigger than baseline (P < 0.01) at the endpoint. At the 1(st) month, the average score of IMGI and the mean score of IIEF statistically increased by 46.2 ± 10.5 (P < 0.01) and 7.6 ± 6.2 (P < 0.01), respectively; the score of BAPS significantly decreased by 18.3 ± 4.5 (P < 0.01). These alterations remained steady during follow-up. Considering the significant penile size improvement, lasting psychological benefit, and low complication rate, PA with HA might serve as an appropriate alternative for patients with SPS.
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spelling pubmed-98094762023-01-04 Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome Zhang, Chun-Long Quan, Yuan Li, He Li, Qing Bai, Wen-Jun Xu, Tao Zhang, Xiao-Wei Asian J Androl Original Article There is no well-established procedure for the management of small penis syndrome (SPS), especially when psychological interventions fail. This study aimed at systematically evaluating the physical and psychological benefits of penile augmentation (PA) using injectable hyaluronic acid (HA) gel. Thirty-eight patients receiving PA with HA gel from January 2017 to March 2020 were included and followed up for 1 year. Penile size, erectile function, and psychological burden measured by the Index of Male Genital Image (IMGI), Index of International Erectile Function (IIEF), and Beliefs about Penis Size (BPAS), respectively, were assessed at the beginning and at 1, 3, 6, and 12 months postinjection. The volume of HA gel injected was 21.5 ± 3.7 ml. Compared to baseline data, flaccid penile girth and length significantly increased by 3.41 ± 0.95 cm (P < 0.01) and 2.55 ± 0.55 cm (P < 0.01) at the 1(st) month postinjection, respectively. At the endpoint, despite attenuations, statistically significant improvements in flaccid penis size were still obtained, namely 2.44 ± 1.14 cm in girth (P < 0.01) and 1.65 ± 0.59 cm in length (P < 0.01). Similarly, erectile penile girth statistically increased by 1.32 ± 1.02 cm (P < 0.01) at the 1(st) month but were only 0.80 ± 0.54 cm bigger than baseline (P < 0.01) at the endpoint. At the 1(st) month, the average score of IMGI and the mean score of IIEF statistically increased by 46.2 ± 10.5 (P < 0.01) and 7.6 ± 6.2 (P < 0.01), respectively; the score of BAPS significantly decreased by 18.3 ± 4.5 (P < 0.01). These alterations remained steady during follow-up. Considering the significant penile size improvement, lasting psychological benefit, and low complication rate, PA with HA might serve as an appropriate alternative for patients with SPS. Wolters Kluwer - Medknow 2022-04-08 /pmc/articles/PMC9809476/ /pubmed/35417989 http://dx.doi.org/10.4103/aja20223 Text en Copyright: ©The Author(s)(2022) https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Zhang, Chun-Long
Quan, Yuan
Li, He
Li, Qing
Bai, Wen-Jun
Xu, Tao
Zhang, Xiao-Wei
Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_full Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_fullStr Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_full_unstemmed Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_short Penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
title_sort penile augmentation with injectable hyaluronic acid gel: an alternative choice for small penis syndrome
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809476/
https://www.ncbi.nlm.nih.gov/pubmed/35417989
http://dx.doi.org/10.4103/aja20223
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