Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction

The interrupted Pummerer reaction of alkynyl sulfoxides with phenols is disclosed. A wide range of benzo[b]furans were efficiently synthesized through unexplored electrophilic activation of the electron-deficient alkynyl sulfinyl group. Based on the good availability of alkynyl sulfoxides, we succes...

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Detalles Bibliográficos
Autores principales: Kobayashi, Akihiro, Matsuzawa, Tsubasa, Hosoya, Takamitsu, Yoshida, Suguru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2023
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809539/
https://www.ncbi.nlm.nih.gov/pubmed/36686947
http://dx.doi.org/10.1039/d2ra07856b
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author Kobayashi, Akihiro
Matsuzawa, Tsubasa
Hosoya, Takamitsu
Yoshida, Suguru
author_facet Kobayashi, Akihiro
Matsuzawa, Tsubasa
Hosoya, Takamitsu
Yoshida, Suguru
author_sort Kobayashi, Akihiro
collection PubMed
description The interrupted Pummerer reaction of alkynyl sulfoxides with phenols is disclosed. A wide range of benzo[b]furans were efficiently synthesized through unexplored electrophilic activation of the electron-deficient alkynyl sulfinyl group. Based on the good availability of alkynyl sulfoxides, we successfully prepared various functionalized benzo[b]furans from readily available alkynes, thiosulfonates, and phenols.
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spelling pubmed-98095392023-01-20 Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction Kobayashi, Akihiro Matsuzawa, Tsubasa Hosoya, Takamitsu Yoshida, Suguru RSC Adv Chemistry The interrupted Pummerer reaction of alkynyl sulfoxides with phenols is disclosed. A wide range of benzo[b]furans were efficiently synthesized through unexplored electrophilic activation of the electron-deficient alkynyl sulfinyl group. Based on the good availability of alkynyl sulfoxides, we successfully prepared various functionalized benzo[b]furans from readily available alkynes, thiosulfonates, and phenols. The Royal Society of Chemistry 2023-01-03 /pmc/articles/PMC9809539/ /pubmed/36686947 http://dx.doi.org/10.1039/d2ra07856b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Kobayashi, Akihiro
Matsuzawa, Tsubasa
Hosoya, Takamitsu
Yoshida, Suguru
Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction
title Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction
title_full Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction
title_fullStr Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction
title_full_unstemmed Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction
title_short Synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted Pummerer reaction
title_sort synthesis of benzo[b]furans from alkynyl sulfoxides and phenols by the interrupted pummerer reaction
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809539/
https://www.ncbi.nlm.nih.gov/pubmed/36686947
http://dx.doi.org/10.1039/d2ra07856b
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