Nucleoporin POM121 signals TFEB-mediated autophagy via activation of SIGMAR1/sigma-1 receptor chaperone by pridopidine

Macroautophagy/autophagy is an essential process for cellular survival and is implicated in many diseases. A critical step in autophagy is the transport of the transcription factor TFEB from the cytosol into the nucleus, through the nuclear pore (NP) by KPNB1/importinβ1. In the C9orf72 subtype of am...

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Detalles Bibliográficos
Autores principales: Wang, Shao-Ming, Wu, Hsiang-En, Yasui, Yuko, Geva, Michal, Hayden, Michael, Maurice, Tangui, Cozzolino, Mauro, Su, Tsung-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809944/
https://www.ncbi.nlm.nih.gov/pubmed/35507432
http://dx.doi.org/10.1080/15548627.2022.2063003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9809944/
https://www.ncbi.nlm.nih.gov/pubmed/35507432
http://dx.doi.org/10.1080/15548627.2022.2063003

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