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Antitumor and off-target effects of cholesterol-conjugated let-7a mimics in an orthotopic hepatocellular carcinoma xenograft nude mouse model

To explore the antitumor and potential off-target effects of systemically delivered cholesterol-conjugated let-7a mimics (Chol-let-7a) and control mimics (Chol-miRCtrl) on hepatocellular carcinoma in vivo. METHODS: The antitumor effects of two intravenous dosing regimens of Chol-let-7a on heptocellu...

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Detalles Bibliográficos
Autores principales:	Guan, Jian, Liu, Mingyang, Li, Xin, Zhou, Liangrui, Dong, Xueyu, Dai, Wei, Xia, Yu, Yang, Tao, Guo, Shaojuan, Li, Xingqi, Han, Yehua, Luo, Yufeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2022
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810003/ https://www.ncbi.nlm.nih.gov/pubmed/36618771 http://dx.doi.org/10.1097/JBR.0000000000000103

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