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Impact of the COVID-19 pandemic and multiplex polymerase chain reaction test on outpatient antibiotic prescriptions for pediatric respiratory infection
This study aimed to evaluate the impact of the prolonged COVID-19 pandemic on outpatient antibiotic prescriptions for pediatric respiratory infections at an acute care hospital in Japan in order to direct future pediatric outpatient antibiotic stewardship. The impact of the COVID-19 pandemic and the...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810151/ https://www.ncbi.nlm.nih.gov/pubmed/36595501 http://dx.doi.org/10.1371/journal.pone.0278932 |
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author | Kitagawa, Daisuke Kitano, Taito Furumori, Madoka Suzuki, Soma Shintani, Yui Nishikawa, Hiroki Suzuki, Rika Yamamoto, Naohiro Onaka, Masayuki Nishiyama, Atsuko Kasamatsu, Takehito Shiraishi, Naoyuki Suzuki, Yuki Nakano, Akiyo Nakano, Ryuichi Yano, Hisakazu Maeda, Koichi Yoshida, Sayaka Nakamura, Fumihiko |
author_facet | Kitagawa, Daisuke Kitano, Taito Furumori, Madoka Suzuki, Soma Shintani, Yui Nishikawa, Hiroki Suzuki, Rika Yamamoto, Naohiro Onaka, Masayuki Nishiyama, Atsuko Kasamatsu, Takehito Shiraishi, Naoyuki Suzuki, Yuki Nakano, Akiyo Nakano, Ryuichi Yano, Hisakazu Maeda, Koichi Yoshida, Sayaka Nakamura, Fumihiko |
author_sort | Kitagawa, Daisuke |
collection | PubMed |
description | This study aimed to evaluate the impact of the prolonged COVID-19 pandemic on outpatient antibiotic prescriptions for pediatric respiratory infections at an acute care hospital in Japan in order to direct future pediatric outpatient antibiotic stewardship. The impact of the COVID-19 pandemic and the FilmArray Respiratory Panel (RP) on outpatient antibiotic prescriptions was assessed from January 2019 to December 2021 using an interrupted time series analysis of children <20 years. The overall antimicrobial prescription rate decreased from 38.7% to 22.4% from the pre-pandemic period to the pandemic. The pandemic (relative risk [RR] level, 0.97 [0.58–1.61]; P = 0.90; RR slope, 1.05 [0.95–1.17] per month; P = 0.310) and FilmArray RP (RR level, 0.90 [0.46–1.75]; P = 0.75; RR slope, 0.95 [0.85–1.06] per month; P = 0.330) had no significant effect on the monthly antibiotic prescription rates. The COVID-19 pandemic was not significantly related to the antibiotic prescription rate, suggesting that it did not impact physicians’ behavior toward antibiotic prescriptions. Replacing rapid antigen tests with the FilmArray RP introduced on December 1, 2020, did not affect the magnitude of the reduction in antibiotic prescription rate for pediatric respiratory infections. |
format | Online Article Text |
id | pubmed-9810151 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-98101512023-01-04 Impact of the COVID-19 pandemic and multiplex polymerase chain reaction test on outpatient antibiotic prescriptions for pediatric respiratory infection Kitagawa, Daisuke Kitano, Taito Furumori, Madoka Suzuki, Soma Shintani, Yui Nishikawa, Hiroki Suzuki, Rika Yamamoto, Naohiro Onaka, Masayuki Nishiyama, Atsuko Kasamatsu, Takehito Shiraishi, Naoyuki Suzuki, Yuki Nakano, Akiyo Nakano, Ryuichi Yano, Hisakazu Maeda, Koichi Yoshida, Sayaka Nakamura, Fumihiko PLoS One Research Article This study aimed to evaluate the impact of the prolonged COVID-19 pandemic on outpatient antibiotic prescriptions for pediatric respiratory infections at an acute care hospital in Japan in order to direct future pediatric outpatient antibiotic stewardship. The impact of the COVID-19 pandemic and the FilmArray Respiratory Panel (RP) on outpatient antibiotic prescriptions was assessed from January 2019 to December 2021 using an interrupted time series analysis of children <20 years. The overall antimicrobial prescription rate decreased from 38.7% to 22.4% from the pre-pandemic period to the pandemic. The pandemic (relative risk [RR] level, 0.97 [0.58–1.61]; P = 0.90; RR slope, 1.05 [0.95–1.17] per month; P = 0.310) and FilmArray RP (RR level, 0.90 [0.46–1.75]; P = 0.75; RR slope, 0.95 [0.85–1.06] per month; P = 0.330) had no significant effect on the monthly antibiotic prescription rates. The COVID-19 pandemic was not significantly related to the antibiotic prescription rate, suggesting that it did not impact physicians’ behavior toward antibiotic prescriptions. Replacing rapid antigen tests with the FilmArray RP introduced on December 1, 2020, did not affect the magnitude of the reduction in antibiotic prescription rate for pediatric respiratory infections. Public Library of Science 2023-01-03 /pmc/articles/PMC9810151/ /pubmed/36595501 http://dx.doi.org/10.1371/journal.pone.0278932 Text en © 2023 Kitagawa et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Kitagawa, Daisuke Kitano, Taito Furumori, Madoka Suzuki, Soma Shintani, Yui Nishikawa, Hiroki Suzuki, Rika Yamamoto, Naohiro Onaka, Masayuki Nishiyama, Atsuko Kasamatsu, Takehito Shiraishi, Naoyuki Suzuki, Yuki Nakano, Akiyo Nakano, Ryuichi Yano, Hisakazu Maeda, Koichi Yoshida, Sayaka Nakamura, Fumihiko Impact of the COVID-19 pandemic and multiplex polymerase chain reaction test on outpatient antibiotic prescriptions for pediatric respiratory infection |
title | Impact of the COVID-19 pandemic and multiplex polymerase chain reaction test on outpatient antibiotic prescriptions for pediatric respiratory infection |
title_full | Impact of the COVID-19 pandemic and multiplex polymerase chain reaction test on outpatient antibiotic prescriptions for pediatric respiratory infection |
title_fullStr | Impact of the COVID-19 pandemic and multiplex polymerase chain reaction test on outpatient antibiotic prescriptions for pediatric respiratory infection |
title_full_unstemmed | Impact of the COVID-19 pandemic and multiplex polymerase chain reaction test on outpatient antibiotic prescriptions for pediatric respiratory infection |
title_short | Impact of the COVID-19 pandemic and multiplex polymerase chain reaction test on outpatient antibiotic prescriptions for pediatric respiratory infection |
title_sort | impact of the covid-19 pandemic and multiplex polymerase chain reaction test on outpatient antibiotic prescriptions for pediatric respiratory infection |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810151/ https://www.ncbi.nlm.nih.gov/pubmed/36595501 http://dx.doi.org/10.1371/journal.pone.0278932 |
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