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Methodological approaches to optimize multiplex oral fluid SARS-CoV-2 IgG assay performance and correlation with serologic and neutralizing antibody responses
BACKGROUND. Oral fluid (hereafter, saliva) is a non-invasive and attractive alternative to blood for SARS-CoV-2 IgG testing; however, the heterogeneity of saliva as a matrix poses challenges for immunoassay performance. OBJECTIVES. To optimize performance of a magnetic microparticle-based multiplex...
Autores principales: | Pisanic, Nora, Antar, Annukka A. R., Kruczynski, Kate, Rivera, Magdielis Gregory, Dhakal, Santosh, Spicer, Kristoffer, Randad, Pranay R., Pekosz, Andrew, Klein, Sabra L., Betenbaugh, Michael J., Detrick, Barbara, Clarke, William, Thomas, David L., Manabe, Yukari C., Heaney, Christopher D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810233/ https://www.ncbi.nlm.nih.gov/pubmed/36597525 http://dx.doi.org/10.1101/2022.12.22.22283858 |
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