Cargando…

Alterations in p53 Influence hTERT, VEGF and MMPs Expression in Oral Cancer Patients

BACKGROUND: Mutant p53 is the crucial molecule in the etiopathogenesis of oral cancer. Therefore, we aimed to evaluate the impact of alterations of the p53 gene and its negative feedback regulator, MDM2, on the expression of hTERT, VEGF, and MMPs; the critical genes involved in oral cancer progressi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Singh, Ragini D, Patel, Kinjal A, Patel, Jayendra B, Patel, Prabhudas S
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	West Asia Organization for Cancer Prevention 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810300/ https://www.ncbi.nlm.nih.gov/pubmed/36172677 http://dx.doi.org/10.31557/APJCP.2022.23.9.3141

Ejemplares similares

Association of Interactions between Metabolic ‘Caretaker’ Genes, p53, MDM2, and Tobacco Use with the Risk of Oral Cancer: A Multifactor Dimensionality Reduction Approach
por: Singh, Ragini D, et al.
Publicado: (2023)

Altered mRNA Expression of Fucosyltransferases and Fucosidase Predicts Prognosis in Human Oral Carcinoma
por: Mehta, Kruti, et al.
Publicado: (2021)

hTERT, MYC and TP53 deregulation in gastric preneoplastic lesions
por: Silva, Tanielly Cristina Raiol, et al.
Publicado: (2012)

The mRNA expression of hTERT in human breast carcinomas correlates with VEGF expression
por: Kirkpatrick, Katharine L, et al.
Publicado: (2004)

A Novel Long Non-Coding RNA in the hTERT Promoter Region Regulates hTERT Expression
por: Malhotra, Sanandan, et al.
Publicado: (2017)

Proteome alteration induced by hTERT transfection of human fibroblast cells
por: Mazzucchelli, Gabriel D, et al.
Publicado: (2008)

An Improved Model for the hTERT Promoter Quadruplex
por: Chaires, Jonathan B., et al.
Publicado: (2014)

Sulforaphane Causes Epigenetic Repression of hTERT Expression in Human Breast Cancer Cell Lines
por: Meeran, Syed M., et al.
Publicado: (2010)

Role of aberrant glycosylation enzymes in oral cancer progression
por: Vajaria, Bhairavi N., et al.
Publicado: (2018)

hTERT promotes tumor angiogenesis by activating VEGF via interactions with the Sp1 transcription factor
por: Liu, Ning, et al.
Publicado: (2016)

Transcriptional Biomarkers in Oral Cancer: An Integrative Analysis and the Cancer Genome Atlas Validation
por: Patel, Kinjal D, et al.
Publicado: (2021)

Telomere length and hTERT in mania and subsequent remission
por: Çinar, Rugül Köse
Publicado: (2017)

Antithetic hTERT Regulation by Androgens in Prostate Cancer Cells: hTERT Inhibition Is Mediated by the ING1 and ING2 Tumor Suppressors
por: Bartsch, Sophie, et al.
Publicado: (2021)

hTERT DNA Methylation Analysis Identifies a Biomarker for Retinoic Acid-Induced hTERT Repression in Breast Cancer Cell Lines
por: Nguyen, Eric, et al.
Publicado: (2022)

Primary and hTERT-Transduced Mesothelioma-Associated Fibroblasts but Not Primary or hTERT-Transduced Mesothelial Cells Stimulate Growth of Human Mesothelioma Cells
por: Ries, Alexander, et al.
Publicado: (2023)

Regulation and clinical potential of telomerase reverse transcriptase (TERT/hTERT) in breast cancer
por: Yang, Ruozhu, et al.
Publicado: (2023)

Dual roles of c-Myc in the regulation of hTERT gene
por: Zhao, Yuanjun, et al.
Publicado: (2014)

The intrabody targeting of hTERT attenuates the immortality of cancer cells
por: Zhu, Xiangying, et al.
Publicado: (2009)

Exploring hTERT promoter methylation in cutaneous T‐cell lymphomas
por: Chebly, Alain, et al.
Publicado: (2021)

Spotlight on hTERT Complex Regulation in Cutaneous T-Cell Lymphomas
por: Ropio, Joana, et al.
Publicado: (2023)

Generation of Immortalised But Unstable Cells after hTERT Introduction in Telomere-Compromised and p53-Deficient vHMECs
por: Bernal, Aina, et al.
Publicado: (2018)

hTERT mRNA dendritic cell vaccination: complete response in a pancreatic cancer patient associated with response against several hTERT epitopes
por: Suso, Else M. Inderberg, et al.
Publicado: (2011)

Widespread CD4+ T-cell reactivity to novel hTERT epitopes following vaccination of cancer patients with a single hTERT peptide GV1001
por: Inderberg-Suso, Else-Marit, et al.
Publicado: (2012)

Tax alters telomerase activity through both quantitative and qualitative hTERT transcriptional dysregulations
por: Karam, Maroun, et al.
Publicado: (2011)

Adipose-Derived Mesenchymal Stem Cell (MSC) Immortalization by Modulation of hTERT and TP53 Expression Levels
por: Rakhmatullina, Aigul R., et al.
Publicado: (2023)

Use of the Comet-FISH Assay to Compare DNA Damage and Repair in p53 and hTERT Genes following Ionizing Radiation
por: McKenna, Declan J., et al.
Publicado: (2012)

Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours
por: Lantuejoul, S, et al.
Publicado: (2004)

Functional and gene expression analysis of hTERT overexpressed endothelial cells
por: Takano, Haruna, et al.
Publicado: (2008)

hTERT promotes cell adhesion and migration independent of telomerase activity
por: Liu, Haiying, et al.
Publicado: (2016)

PCDH10 Interacts With hTERT and Negatively Regulates Telomerase Activity
por: Zhou, Li-Na, et al.
Publicado: (2015)

Transcription Regulation of the Human Telomerase Reverse Transcriptase (hTERT) Gene
por: Ramlee, Muhammad Khairul, et al.
Publicado: (2016)

A Novel Hybrid Promoter ARE-hTERT for Cancer Gene Therapy
por: Kalinichenko, S. V., et al.
Publicado: (2017)

CDK1 dependent phosphorylation of hTERT contributes to cancer progression
por: Yasukawa, Mami, et al.
Publicado: (2020)

The hTERT core promoter forms three parallel G-quadruplexes
por: Monsen, Robert C, et al.
Publicado: (2020)

Targeting HMGB3/hTERT axis for radioresistance in cervical cancer
por: Li, Zongjuan, et al.
Publicado: (2020)

Hypermethylation of the hTERT promoter inhibits the expression of telomerase activity in normal oral fibroblasts and senescent normal oral keratinocytes
por: Shin, K-H, et al.
Publicado: (2003)

Genome-protective topoisomerase 2a-dependent G2 arrest requires p53 in hTERT-positive cancer cells
por: Lockwood, Nicola, et al.
Publicado: (2022)

Differential DNA Methylation of THOR and hTAPAS in the Regulation of hTERT and the Diagnosis of Cancer
por: Ott, Pauline, et al.
Publicado: (2022)

Receptor C(k)-dependent signaling regulates hTERT gene transcription
por: Sikand, Kavleen, et al.
Publicado: (2006)

CTCF binds the proximal exonic region of hTERT and inhibits its transcription
por: Renaud, Stéphanie, et al.
Publicado: (2005)

Cannot write session to /tmp/vufind_sessions/sess_hjourqlur5egu5qmsgairuvdeo