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The role of SWI/SNF chromatin remodelers in the repair of DNA double strand breaks and cancer therapy
Switch/Sucrose non-fermenting (SWI/SNF) chromatin remodelers hydrolyze ATP to push and slide nucleosomes along the DNA thus modulating access to various genomic loci. These complexes are the most frequently mutated epigenetic regulators in human cancers. SWI/SNF complexes are well known for their fu...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810387/ https://www.ncbi.nlm.nih.gov/pubmed/36605718 http://dx.doi.org/10.3389/fcell.2022.1071786 |