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A multi-scale model explains oscillatory slowing and neuronal hyperactivity in Alzheimer’s disease

Alzheimer’s disease is the most common cause of dementia and is linked to the spreading of pathological amyloid-β and tau proteins throughout the brain. Recent studies have highlighted stark differences in how amyloid-β and tau affect neurons at the cellular scale. On a larger scale, Alzheimer’s pat...

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Detalles Bibliográficos
Autores principales: Alexandersen, Christoffer G., de Haan, Willem, Bick, Christian, Goriely, Alain
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810432/
https://www.ncbi.nlm.nih.gov/pubmed/36596460
http://dx.doi.org/10.1098/rsif.2022.0607