Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity

Glycogen synthase kinase-3β (GSK-3β) is an important serine/threonine kinase that implicates in multiple cellular processes and links with the neurodegenerative diseases including Alzheimer’s disease (AD). In this study, structure-based virtual screening was performed to search database for compound...

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Detalles Bibliográficos
Autores principales: Lin, Chih-Hsin, Hsieh, Yu-Shao, Sun, Ying-Chieh, Huang, Wun-Han, Chen, Shu-Ling, Weng, Zheng-Kui, Lin, Te-Hsien, Wu, Yih-Ru, Chang, Kuo-Hsuan, Huang, Hei-Jen, Lee, Guan-Chiun, Hsieh-Li, Hsiu Mei, Lee-Chen, Guey-Jen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Society of Applied Pharmacology 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810448/
https://www.ncbi.nlm.nih.gov/pubmed/35790892
http://dx.doi.org/10.4062/biomolther.2022.035

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810448/
https://www.ncbi.nlm.nih.gov/pubmed/35790892
http://dx.doi.org/10.4062/biomolther.2022.035

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