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Virtual Screening and Testing of GSK-3 Inhibitors Using Human SH-SY5Y Cells Expressing Tau Folding Reporter and Mouse Hippocampal Primary Culture under Tau Cytotoxicity
Glycogen synthase kinase-3β (GSK-3β) is an important serine/threonine kinase that implicates in multiple cellular processes and links with the neurodegenerative diseases including Alzheimer’s disease (AD). In this study, structure-based virtual screening was performed to search database for compound...
Autores principales: | Lin, Chih-Hsin, Hsieh, Yu-Shao, Sun, Ying-Chieh, Huang, Wun-Han, Chen, Shu-Ling, Weng, Zheng-Kui, Lin, Te-Hsien, Wu, Yih-Ru, Chang, Kuo-Hsuan, Huang, Hei-Jen, Lee, Guan-Chiun, Hsieh-Li, Hsiu Mei, Lee-Chen, Guey-Jen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Society of Applied Pharmacology
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9810448/ https://www.ncbi.nlm.nih.gov/pubmed/35790892 http://dx.doi.org/10.4062/biomolther.2022.035 |
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